Myasthenia gravis associated with thymic neoplasia in a cat

被引:4
作者
Meeking, Susan A. [1 ]
Prittie, Jennifer [1 ]
Barton, Linda [1 ]
机构
[1] Anim Med Ctr, New York, NY 10065 USA
关键词
paraneoplastic syndrome; thymoma; postoperative complication;
D O I
10.1111/j.1476-4431.2008.00290.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
To describe acute myasthenia gravis (MG) in the postoperative period following removal of a thymoma in an adult cat. A 6-year-old spayed female domestic short haired cat weighing 6.4 kg was referred for workup and treatment of a cranial mediastinal mass. Thoracoscopic biopsies confirmed the diagnosis of thymoma. Median sternotomy was performed and approximately 95% of the mass was surgically excised. Postoperatively the cat became remarkably weak and hypercapneic. A presumptive diagnosis of MG was made following a positive response to edrophonium injection (Tensilon test). An elevated serum acetylcholine receptor antibody level was consistent with a diagnosis of MG. Initial treatment consisted of neostigmine, followed by corticosteroids and pyridostigmine. The cat responded well to therapy. This report describes a rare syndrome of postoperative weakness due to development of MG following incomplete removal of a thymoma. Post-thymectomy weakness associated with MG has been reported in dogs and is not well described in cats.
引用
收藏
页码:177 / 183
页数:7
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