Mini-emulsion solvent evaporation: a simple and versatile way to magnetic nanosensors

被引:21
|
作者
Mistlberger, Guenter [1 ]
Medina-Castillo, Antonio L. [2 ]
Borisov, Sergey M. [1 ]
Mayr, Torsten [1 ]
Fernandez-Gutierrez, Alberto [2 ]
Fernandez-Sanchez, Jorge F. [2 ]
Klimant, Ingo [1 ]
机构
[1] Graz Univ Technol, Inst Analyt Chem & Food Chem, A-8010 Graz, Austria
[2] Univ Granada, Dept Analyt Chem, E-18071 Granada, Spain
关键词
Magnetic optical sensor particles; Oxygen sensor; pH sensor; Light harvesting; Miniemulsion solvent evaporation; Nanosensor; SINGLE LIVING CELLS; OPTICAL NANOSENSORS; CHEMICAL-ANALYSIS; DISSOLVED-OXYGEN; PEBBLE SENSORS; DRUG-DELIVERY; NANOPARTICLES; FABRICATION; PH; PRECIPITATION;
D O I
10.1007/s00604-010-0492-0
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Magnetic optical sensor particles were prepared using a mini-emulsion solvent evaporation (MESE) technique. The resulting nanoparticles (NPs) have diameters around 100 nm and relatively narrow size distribution (PDI < 0.2). Incorporation of probes for oxygen or pH resulted in magnetic sensor particles for bioprocess monitoring and imaging applications. The MESE technique yields sensing NPs in higher quantities than obtained by a previously reported nano-precipitation method, and the size of the NPs is smaller than that of particles made by spray-drying of sensor cocktails. Moreover, the technique is flexible in terms of polymers, solvents and indicators used in that it may be applied-at least in principle-to numerous combinations of two-phase systems.
引用
收藏
页码:299 / 308
页数:10
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