Pathogenicity of 2 Porcine Deltacoronavirus Strains in Gnotobiotic Pigs

被引：180

作者：

Jung, Kwonil ^{[1
]}

Hu, Hui ^{[1
]}

Eyerly, Bryan ^{[1
]}

Lu, Zhongyan ^{[1
]}

Chepngeno, Juliet ^{[1
]}

Saif, Linda J. ^{[1
]}

机构：

[1] Ohio State Univ, Wooster, OH 44691 USA

来源：

EMERGING INFECTIOUS DISEASES | 2015年 / 21卷 / 04期

关键词：

D O I：

10.3201/eid2104.141859

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21-120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.

引用

收藏

页码：650 / 654

页数：5

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