Pathogenicity of 2 Porcine Deltacoronavirus Strains in Gnotobiotic Pigs

被引：174
作者：
Jung, Kwonil [1 ]
Hu, Hui [1 ]
Eyerly, Bryan [1 ]
Lu, Zhongyan [1 ]
Chepngeno, Juliet [1 ]
Saif, Linda J. [1 ]
机构：
[1] Ohio State Univ, Wooster, OH 44691 USA
来源：
EMERGING INFECTIOUS DISEASES | 2015年 / 21卷 / 04期
关键词：
D O I：
10.3201/eid2104.141859
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21-120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.
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收藏
页码：650 / 654
页数：5
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