Does a Decrease of NK Cells in the Appendix Increase the Risk of Developing Colon Cancer?

被引：5

作者：

Cai Yuan-Kun ^{[1
]}

Ye Tao ^{[1
]}

机构：

[1] Fudan Univ, Dept Gen Surg, Peoples Hosp Shanghai 5, Shanghai 200240, Peoples R China

来源：

HEPATO-GASTROENTEROLOGY | 2012年 / 59卷 / 118期

关键词：

Natural killer cell; Appendix; Right colon cancer; Immunity; COLORECTAL-CARCINOMA; APPENDECTOMY;

D O I：

10.5754/hge10781

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background/Aims: Epidemiological studies indicate that relevance between appendix and colon cancer is controversial, but unfortunately, there is no data based on examination of immune indicator to reveal the relativity. Methodology: This study explored the relationship between appendix immunity and the right colon cancer by detecting the presence of NK cells in appendix tissues with immunohistochemistry. Results: The number of NK cells in the appendix tissue was the highest in patients with appendix inflammation (37.2 +/- 1.1), while lowest in patients with colon cancer and normal appendix (30.9 +/- 1.7). Conclusions: The decrease of NK cells in the appendix tissue is correlated with the increased incidence of right colon cancer.

引用

页码：1819 / 1821

页数：3

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