Radical Addition of Silanes to Alkenes Followed by Oxidation

被引：5

作者：

Palframan, Matthew J. ^{[1
]}

Parsons, Andrew F. ^{[1
]}

Johnson, Paul ^{[2
]}

机构：

[1] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

[2] AstraZeneca, Macclesfield SK10 4TF, Cheshire, England

来源：

SYNLETT | 2011年 / 19期

基金：

英国工程与自然科学研究理事会;

关键词：

addition reaction; alcohol; alkene; radical reaction; silane; SILYLATED CYCLOHEXADIENES; SILAFUNCTIONAL COMPOUNDS; CHAIN HYDROSILYLATION; ORGANIC-SYNTHESIS; PETERSON REACTION; CYCLIZATION; BONDS; AGENT;

D O I：

10.1055/s-0031-1289568

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Phenyldimethylsilane and trichlorosilane are shown to undergo efficient radical hydrosilylation reactions, on reaction with various alkenes, using triethylborane as the initiator. Adducts from the trichlorosilane reactions can be oxidised to afford alcohols in good yields. This two-step process leads to the anti-Markovnikov hydration of alkenes.

引用

页码：2811 / 2814

页数：4

共 26 条

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