The role of drinking water in the transmission of antimicrobial-resistant E. coli

被引：50

作者：

Coleman, B. L. ^{[1
,2
]}

Salvadori, M. I. ^{[3
,4
]}

McGeer, A. J. ^{[1
,2
]}

Sibley, K. A. ^{[5
]}

Neumann, N. F. ^{[6
,7
]}

Bondy, S. J. ^{[2
]}

Gutmanis, I. A. ^{[4
,8
]}

McEwen, S. A. ^{[9
]}

Lavoie, M. ^{[7
]}

Strong, D. ^{[7
]}

Johnson, I. ^{[2
,10
]}

Jamieson, F. B. ^{[1
,2
,10
]}

Louie, M. ^{[5
,7
]}

机构：

[1] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada

[2] Univ Toronto, Toronto, ON, Canada

[3] Childrens Hosp Western Ontario, London, ON, Canada

[4] Univ Western Ontario, London, ON, Canada

[5] Univ Calgary, Calgary, AB, Canada

[6] Univ Alberta, Edmonton, AB, Canada

[7] Alberta Hlth Serv, Edmonton, AB, Canada

[8] St Josephs Hlth Care, London, ON, Canada

[9] Univ Guelph, Guelph, ON N1G 2W1, Canada

[10] Ontario Agcy Hlth Protect & Promot, Toronto, ON, Canada

来源：

EPIDEMIOLOGY AND INFECTION | 2012年 / 140卷 / 04期

基金：

加拿大健康研究院;

关键词：

Antibiotic resistance; enteric bacteria; epidemiology; Escherichia coli; water (safe); FECAL ESCHERICHIA-COLI; ANTIBIOTIC-RESISTANCE; RISK-FACTORS; COLONIZATION; COMMUNITY; CHILDREN; ADULTS; VEGETARIANS; AMPICILLIN; EMERGENCE;

D O I：

10.1017/S0950268811001038

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To determine whether drinking water contaminated with antimicrobial-resistant E. coli is associated with the carriage of resistant E. coli, selected households sending water samples to Ontario and Alberta laboratories in 2005-2006 were asked to participate in a cross-sectional study. Household members aged >= 12 years were asked to complete a questionnaire and to submit a rectal swab. In 878 individuals, 41% carried a resistant strain of E. coli and 28% carried a multidrug-resistant strain. The risk of carriage of resistant E. coli was 1.26 times higher for users of water contaminated with resistant E. coli. Other risk factors included international travel [prevalence ratio (PR) 1.33], having a child in nappies (PR 1.33), being male (PR 1.33), and frequent handling of raw red meats (PR 1.10). Protecting private water sources (e.g. by improving systems to test and treat them) may help slow the emergence of antimicrobial resistance in E. coli.

引用

页码：633 / 642

页数：10

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