Hemophagocytic lymphohistiocytosis associated with H1N1 virus infection and visceral leishmaniasis in a 4.5-month-old infant

被引：11
作者：
Ay, Yilmaz [2 ]
Yildiz, Basak [1 ]
Tuhan, Hale
Karapinar, Deniz Yilmaz [2 ]
Vardar, Fadil [1 ]
机构：
[1] Ege Univ, Div Pediat Infect Dis, Fac Med, TR-35510 Izmir, Turkey
[2] Ege Univ, Div Pediat Hematol, Fac Med, TR-35510 Izmir, Turkey
来源：
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2012年 / 45卷 / 03期
关键词：
H1N1; virus; Visceral leishmaniasis; Hemophagocytic lymphohistiocytosis;
D O I：
10.1590/S0037-86822012000300026
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
We present a case of a 4.5-month-old boy from Turkey with hemophagocytic lymphohistiocytosis (HLH) associated with H1N1 virus and Leishmania spp. coinfection. Because visceral leishmaniasis can mimic hematologic disorders like HLH, it is important to rule out this clinical condition before starting immunosuppressive therapy. In our case, treatment with liposomal amphotericin B resulted in a dramatic resolution of clinical and laboratory abnormalities.
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收藏
页码：405 / 406
页数：2
相关论文
共 10 条
  • [1] Hemophagocytic syndrome associated with visceral leishmaniasis
    Agarwal S.
    Narayan S.
    Sharma S.
    Kahkashan E.
    Patwari A.K.
    [J]. The Indian Journal of Pediatrics, 2006, 73 (5) : 445 - 446
  • [2] Haemophagocytic syndrome and HIV
    Doyle, Tomas
    Bhagani, Sanjay
    Cwynarski, Kate
    [J]. CURRENT OPINION IN INFECTIOUS DISEASES, 2009, 22 (01) : 1 - 6
  • [3] Treatment of Epstein-Barr Virus-related Hemophagocytic Lymphohistiocytosis (EBV-HLH); Update 2010
    Imashuku, Shinsaku
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2011, 33 (01) : 35 - 39
  • [4] Visceral leishmanisasis in paeditrics
    Kafetzis, DA
    Maltezou, HC
    [J]. CURRENT OPINION IN INFECTIOUS DISEASES, 2002, 15 (03) : 289 - 294
  • [5] Hemophagocytic lymphohistiocytosis associated with Epstein Barr virus and Leishmania donovani coinfection in a child from Cyprus
    Koliou, Maria G.
    Soteriades, Elpidoforos S.
    Ephros, Moshe
    Mazeris, Apostolos
    Antoniou, Maria
    Elia, Avraam
    Novelli, Vas
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2008, 30 (09) : 704 - 707
  • [6] Ortega-Barria E, 2008, PRINCIPLES PRACTICE, P1248
  • [7] Hemophagocytic lymphohistiocytosis associated with visceral leishmaniasis:: A case report
    Özyürek, E
    Özçay, F
    Yilmaz, B
    Özbek, N
    [J]. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2005, 22 (05) : 409 - 414
  • [8] Microbiological Findings and Treatment of EBV-Associated Hemophagocytic Lymphohistiocytosis: A Case Report
    Przybylski, Maciej
    Dzieciatkowski, Tomasz
    Zdunczyk, Dorota
    Jedrzejczak, Wieslaw Wiktor
    Luczak, Miroslaw
    [J]. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2010, 58 (03) : 247 - 252
  • [9] Visceral leishmaniasis associated hemophagocytic lymphohistiocytosis - Case report and systematic review
    Rajagopala, Srinivas
    Dutta, Usha
    Chandra, K. S. Poorna
    Bhatia, Prateek
    Varma, Neelam
    Kochhar, Rakesh
    [J]. JOURNAL OF INFECTION, 2008, 56 (05) : 381 - 388
  • [10] Hemophagocytic lymphohistiocytosis associated with visceral leishmaniasis
    Tapisiz, Anil
    Belet, Nursen
    Ciftci, Ergin
    Ince, Erdal
    Dogru, Uelker
    [J]. JOURNAL OF TROPICAL PEDIATRICS, 2007, 53 (05) : 359 - 361
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