The Rickettsioses A Practical Update

被引:133
作者
Blanton, Lucas S. [1 ]
机构
[1] Univ Texas Med Branch, Dept Internal Med, Div Infect Dis, 301 Univ Blvd, Galveston, TX 77555 USA
基金
美国国家卫生研究院;
关键词
Spotted fever group rickettsioses; Rocky mountain spotted fever; Rickettsia rickettsii; Epidemic typhus; Rickettsia prowazekii; Murine typhus; Rickettsia typhi; Vector-borne disease; MOUNTAIN-SPOTTED-FEVER; TYPHUS GROUP RICKETTSIOSIS; ENDEMIC AREA-ARIZONA; SHELL-VIAL CULTURE; REAL-TIME PCR; MURINE TYPHUS; TICK BITE; PARKERI RICKETTSIOSIS; RISK-FACTORS; BORNE RICKETTSIOSES;
D O I
10.1016/j.idc.2018.10.010
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Rickettsia are small, obligately intracellular, gram-negative bacilli. They are distributed among a variety of hematophagous arthropod vectors and cause illness throughout the world. Rickettsioses present as an acute undifferentiated febrile illness and are often accompanied by headache, myalgias, and malaise. Cutaneous manifestations include rash and eschar, which both occur at varying incidence depending on the infecting species. Serology is the mainstay of diagnosis, and the indirect immunofluorescence assay is the test of choice. Reactive antibodies are seldom present during early illness, so testing should be performed on both acute-phase and convalescent-phase sera. Doxycycline is the treatment of choice.
引用
收藏
页码:213 / +
页数:18
相关论文
共 96 条
[1]   Rocky Mountain spotted fever in Mexico: past, present, and future [J].
Alvarez-Hernandez, Gerardo ;
Gonzalez Roldan, Jesus Felipe ;
Hernandez Milan, Nestor Saul ;
Ryan Lash, R. ;
Barton Behravesh, Casey ;
Paddock, Christopher D. .
LANCET INFECTIOUS DISEASES, 2017, 17 (06) :E189-E196
[2]   The History of Epidemic Typhus [J].
Angelakis, Emmanouil ;
Bechah, Yassina ;
Raoult, Didier .
MICROBIOLOGY SPECTRUM, 2016, 4 (04)
[3]  
[Anonymous], 1994, Wkly Epidemiol Rec, V69, P259
[4]   Randomized Trial of Clarithromycin for Mediterranean Spotted Fever [J].
Anton, Esperanca ;
Munoz, Tomas ;
Javier Traveria, Francisco ;
Navarro, Gemma ;
Font, Bernat ;
Sanfeliu, Isabel ;
Segura, Ferran .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2016, 60 (03) :1642-1645
[5]   LONG-TERM SEQUELAE OF ROCKY-MOUNTAIN-SPOTTED-FEVER [J].
ARCHIBALD, LK ;
SEXTON, DJ .
CLINICAL INFECTIOUS DISEASES, 1995, 20 (05) :1122-1125
[6]   Epidemic typhus [J].
Bechah, Yossina ;
Capo, Christian ;
Mege, Jean-Louis ;
Raoult, Didier .
LANCET INFECTIOUS DISEASES, 2008, 8 (07) :417-426
[7]   Sennetsu Neorickettsiosis, Spotted Fever Group, and Typhus Group Rickettsioses in Three Provinces in Thailand [J].
Bhengsri, Saithip ;
Baggett, Henry C. ;
Edouard, Sophie ;
Dowel, Scott F. ;
Dasch, Gregory A. ;
Fisk, Tami L. ;
Raoult, Didier ;
Parola, Philippe .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2016, 95 (01) :43-49
[8]  
Biggs HM, 2016, MMWR RECOMM REP, V65, P1, DOI 10.15585/mmwr.rr6502a1
[9]   Limited Evidence for Rickettsia felis as a Cause of Zoonotic Flea-Borne Rickettsiosis in Southern California [J].
Billeter, Sarah A. ;
Metzger, Marco E. .
JOURNAL OF MEDICAL ENTOMOLOGY, 2017, 54 (01) :4-7
[10]   Evaluation of a new serological test for the detection of anti-Coxiella and anti-Rickettsia antibodies [J].
Bizzini, Alain ;
Peter, Olivier ;
Baud, David ;
Edouard, Sophie ;
Meylan, Pascal ;
Greub, Gilbert .
MICROBES AND INFECTION, 2015, 17 (11-12) :811-816