An improved method for synthesizing N,N′-dicarboxymethylchitosan

被引：22

作者：

An, N. T. ^{[1
]}

Dung, P. L. ^{[1
]}

Thien, D. T. ^{[1
]}

Dong, N. T. ^{[1
]}

Nhi, T. T. Y. ^{[1
]}

机构：

[1] VAST, Inst Chem, Nat Polymer Lab, Hanoi 10600, Vietnam

来源：

CARBOHYDRATE POLYMERS | 2008年 / 73卷 / 02期

关键词：

water-soluble chitosan; N-monocarboxymethylchitosan; N; '-dicarboxymethylchitosan; osteogenesis agent; chelating agent;

D O I：

10.1016/j.carbpol.2007.11.025

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Fully substituted N,N'-dicarboxymethylchitosan was obtained by the alkylation of chitosan at pH 8-8.5 and 90 degrees C using a monochloroacetic acid:chitosan weight ratio of 4:1. The water-soluble derivative is a chelating agent suitable for treatment of osteogenis or other applications involving chelation. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：261 / 264

页数：4

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