Subclinical elevations of thyroid-stimulating hormone and assisted reproductive technology outcomes

被引:68
作者
Michalakis, Konstantinos G. [1 ]
Mesen, Tolga B. [1 ,2 ]
Brayboy, LynaeM. [1 ,3 ]
Yu, Bo [1 ]
Richter, Kevin S. [4 ]
Levy, Michael [4 ]
Widra, Eric [4 ]
Segars, James H. [1 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Reprod & Adult Endocrinol, NIH, Bethesda, MD USA
[2] Carolinas Med Ctr, Dept Obstet & Gynecol, Charlotte, NC 28203 USA
[3] Abington Mem Hosp, Dept Obstet & Gynecol, Abington, PA 19001 USA
[4] Shady Grove Fertil Reprod Sci Ctr, Rockville, MD USA
基金
美国国家卫生研究院;
关键词
TSH; autoimmunity; ART; subclinical hypothyroidism; diminished ovarian reserve; IN-VITRO FERTILIZATION; INFERTILE WOMEN; PREGNANCY; HYPOTHYROIDISM; AUTOIMMUNITY; DISORDERS; RISK; TSH;
D O I
10.1016/j.fertnstert.2011.02.056
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The prevalence of moderately elevated TSH levels consistent with subclinical hypothyroidism (2.5-4.0 mu IU/mL) was 23% in a cohort of 1,231 women pursuing assisted reproductive technologies. Preconception elevated levels of TSH were associated with diminished ovarian reserve but were not associated with adverse assisted reproductive technology or pregnancy outcomes. (Fertil Steril (R) 2011;95:2634-7. (C) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码:2634 / 2637
页数:4
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