Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene

被引：0
作者：
Olsson, PG
Tsujioka, H
Narisawa, S
Goldberg, E
Millán, JL
机构：
[1] Burnham Inst, La Jolla, CA 92037 USA
[2] Umea Univ, Med Genet, Dept Med Biosci, S-90187 Umea, Sweden
[3] Northwestern Univ, Dept Biochem Mol Biol & Cell Biol, Evanston, IL USA
来源：
JOURNAL OF ANDROLOGY | 2003年 / 24卷 / 06期
关键词：
isozyme; restriction maps;
D O I：
暂无
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
We have cloned and sequenced the entire mouse ldhc gene and mapped it physically in relation to the somatic ldha gene. The 2 genes were found to be oriented in head-to-tail fashion with about a 6-kilobase (kb) distance between the 3' end of ldha and the 5' end of ldhc. The ldhc gene is composed of 43% repetitive elements compared to only 16% in the ldha gene. Despite the close physical distance of mouse ldha and ldhc, the 2 genes have a very different content of repetitive elements, and this most likely reflects different levels of selective pressure.
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页码：918 / 920
页数：3
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