Multicomponent reactions and ionic liquids: a perfect synergy for eco-compatible heterocyclic synthesis

被引：416

作者：

Isambert, Nicolas ^{[1
]}

Duque, Maria del Mar Sanchez ^{[1
]}

Plaquevent, Jean-Christophe ^{[2
]}

Genisson, Yves ^{[2
]}

Rodriguez, Jean ^{[1
]}

Constantieux, Thierry ^{[1
]}

机构：

[1] Aix Marseille Univ, CNRS, Inst Sci Mol Marseille, UMR 6263,ISm2,Ctr St Jeorme,Serv 531, F-13397 Marseille 20, France

[2] Univ Toulouse 3, CNRS, LSPCMIB, UMR 5068, F-31062 Toulouse 9, France

来源：

CHEMICAL SOCIETY REVIEWS | 2011年 / 40卷 / 03期

关键词：

ONE-POT SYNTHESIS; CATALYZED BIGINELLI REACTION; 3-COMPONENT SYNTHESIS; SUPPORTED SYNTHESIS; FACILE SYNTHESIS; GREEN SYNTHESIS; EFFICIENT; DERIVATIVES; TEMPERATURE; PYRIDINES;

D O I：

10.1039/c0cs00013b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The efficiency of a chemical synthesis can be nowadays measured, not only by parameters like selectivity and overall yield, but also by its raw material, time, human resources and energy requirements, as well as the toxicity and hazard of the chemicals and the protocols involved. The development of multicomponent reactions (MCRs) in the presence of task-specific ionic liquids (ILs), used not only as environmentally benign reaction media, but also as catalysts, is a new approach that meet with the requirements of sustainable chemistry. The aim of this tutorial review is to highlight the synergistic effect of the combined use of MCRs and ILs for the development of new eco-compatible methodologies for heterocyclic chemistry.

引用

页码：1347 / 1357

页数：11

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