Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders

被引:104
|
作者
Cuéllar, MJ [1 ]
Giner, RM [1 ]
Recio, MC [1 ]
Máñez, S [1 ]
Ríos, JL [1 ]
机构
[1] Univ Valencia, Fac Farm, Dept Farmacol, E-46100 Burjassot, Valencia, Spain
关键词
Cassia angustifolia; Coptis chinensis; Phellodendron amurense; Rheum palmatum; Scutellaria baicalensis; anti-inflammatory activity;
D O I
10.1016/S0367-326X(00)00305-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The topical anti-inflammatory activity of extracts from Cassia angustifolia, Rheum palmatum, Coptis chinensis, Phellodendron amurense and Scutellaria baicalensis, plants used in traditional East Asian medicine against different skin disorders, was studied. Though in different degree, all the extracts significantly inhibited the edema induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), in both single or multiple application, oxazolone, and arachidonic acid (AA). None of the extracts inhibited in vitro the activity of phospholipase A(2) (PLA(2)) from Naja naja. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:221 / 229
页数:9
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