In 2009, the CPC Central Committee issued the "on the deepening of the reform of the medical and health system (2009-2011), the focus of the implementation of the program," a comprehensive start health care reform. Along with the advancement of health care reform, China's basic medical security system has been improved, the medical environment and medical service level is gradually improving. At the same time, the demand for medical services is growingand there is still a big contradiction between the medical and health resources and the public health needs. In order to further deepen the reform of the medical and health system, to achieve the goal of all people medical, 2012, the State Council promulgated the "sanitary cause development" 1025 "planning", clearly put forward to strengthen the regional information platform construction, and promote the medical and health information resources sharing of new medical guidelines. This article is from the new medical reform in the context of regional medical information construction, in the exploration of regional medical information construction to promote the role of the new health care reform, the main direction of future regional wisdom medical information construction, to establish the electronic health records and electronic medical records, increase investment, establish a platform for intelligent networking, Central Hospital and community hospitals, regional collaborative service classification system, to further accelerate the sinking of quality medical resources in China, to achieve a comprehensive medical services in China.