Lipid membranes with grafted polymers: physicochemical aspects

被引：195
作者：
Marsh, D
Bartucci, R
Sportelli, L
机构：
[1] Max Planck Inst Biophys Chem, Abt Spektroskopie, D-37077 Gottingen, Germany
[2] Univ Calabria, Dipartimento Fis, I-87036 Arcavacata Di Rende, CS, Italy
[3] Univ Calabria, Unita INFM, I-87036 Arcavacata Di Rende, CS, Italy
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 2003年 / 1615卷 / 1-2期
关键词：
lateral pressure; elastic constant; bilayer-bilayer interaction; protein adsorption; steric stabilisation; polyethyleneglycol;
D O I：
10.1016/S0005-2736(03)00197-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Membranes grafted with water-soluble polymers resist protein adsorption and adhesion to cellular surfaces. Liposomes with surface-grafted polymers therefore find applications in drug delivery. The physicochemical properties of polymer-grafted lipid membranes are reviewed with mean-field and scaling theories from polymer physics. Topics covered are: mushroom-brush transitions, membrane expansion and elasticity, bilayer-micelle transitions, membrane-membrane interactions and protein-membrane interactions. (C) 2003 Elsevier B.V All rights reserved.
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收藏
页码：33 / 59
页数：27
相关论文
共 51 条
[1]   ADSORPTION OF CHAIN MOLECULES WITH A POLAR HEAD A-SCALING DESCRIPTION [J].
ALEXANDER, S .
JOURNAL DE PHYSIQUE, 1977, 38 (08) :983-987
[2]  
[Anonymous], 1971, PRINCIPLES POLYM CHE
[3]   Enhancement of the phase transition permeability of DPPC liposomes by incorporation of MPPC: A new temperature-sensitive liposome for use with mild hyperthermia [J].
Anyarambhatla, GR ;
Needham, D .
JOURNAL OF LIPOSOME RESEARCH, 1999, 9 (04) :491-506
[4]   The effects of ethylene oxide containing lipopolymers and tri-block copolymers on lipid bilayers of dipalmitoylphosphatidylcholine [J].
Baekmark, TR ;
Pedersen, S ;
Jorgensen, K ;
Mouritsen, OG .
BIOPHYSICAL JOURNAL, 1997, 73 (03) :1479-1491
[5]   Interaction of human serum albumin with membranes containing polymer-grafted lipids: spin-label ESR studies in the mushroom and brush regimes [J].
Bartucci, R ;
Pantusa, M ;
Marsh, D ;
Sportelli, L .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2002, 1564 (01) :237-242
[6]   Molecular and mesoscopic properties of hydrophilic polymer-grafted phospholipids mixed with phosphatidylcholine in aqueous dispersion:: Interaction of dipalmitoyl N-poly(ethylene glycol) phosphatidylethanolamine with dipalmitoylphosphatidylcholine studied by spectrophotometry and spin-label electron spin resonance [J].
Belsito, S ;
Bartucci, R ;
Montesano, G ;
Marsh, D ;
Sportelli, L .
BIOPHYSICAL JOURNAL, 2000, 78 (03) :1420-1430
[7]   PHYSICAL-PROPERTIES OF THE FLUID LIPID-BILAYER COMPONENT OF CELL-MEMBRANES - A PERSPECTIVE [J].
BLOOM, M ;
EVANS, E ;
MOURITSEN, OG .
QUARTERLY REVIEWS OF BIOPHYSICS, 1991, 24 (03) :293-397
[8]  
Cevc G, 1987, PHOSPHOLIPID BILAYER
[9]   STATISTICS OF MACROMOLECULAR SOLUTIONS TRAPPED IN SMALL PORES [J].
DAOUD, M ;
DEGENNES, PG .
JOURNAL DE PHYSIQUE, 1977, 38 (01) :85-93
[10]  
de Gennes P.G., 1979, SCALING CONCEPTS POL
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