SYNTHESIS AND CHARACTERIZATION OF MUC-1 FUNCTIONALIZED GOLD NANOPARTICLES

被引：0

作者：

Matea, Cristian T. ^{[1
]}

Mocan, Teodora ^{[1
,2
]}

Tabaran, Flaviu ^{[1
,3
]}

Pop, Teodora ^{[4
]}

Mosteanu, Ofelia ^{[4
]}

Mocan, Lucian ^{[1
,5
]}

Zdrehus, Claudiu ^{[5
]}

机构：

[1] Octavian Fodor Gastroenterol Inst, Dept Nanomed, Cluj Napoca, Romania

[2] Iuliu Hatieganu Univ Med & Pharm, Dept Physiol, Cluj Napoca, Romania

[3] Univ Agr Sci & Vet Med, Fac Vet Med, Dept Pathol, Cluj Napoca, Romania

[4] Iuliu Hatieganu Univ Med & Pharm, Gastroenterol Dept 3, Cluj Napoca, Romania

[5] Iuliu Hatieganu Univ Med & Pharm, Surg Clin 3, Cluj Napoca, Romania

来源：

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA | 2018年 / 63卷 / 03期

关键词：

gold nanoparticles; functionalization; MUC-1; peptide; SERUM-ALBUMIN; DELIVERY; CITRATE;

D O I：

10.24193/subbchem.2018.3.10

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Gold nanoparticles have been functionalized with the biologically active MUC-1 peptide conjugated to KLH and the obtained bionanostructure was characterized using an array of techniques such as: UV-Vis and ATR-FT-IR spectroscopy, dynamic light scattering (DLS) and atomic force microscopy (AFM). A 54 nm monodisperse bio-nanostructure with high aqueous stability was obtained.

引用

页码：129 / 135

页数：7

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