SYNTHESIS AND CHARACTERIZATION OF MUC-1 FUNCTIONALIZED GOLD NANOPARTICLES

被引：0
|
作者：
Matea, Cristian T. [1 ]
Mocan, Teodora [1 ,2 ]
Tabaran, Flaviu [1 ,3 ]
Pop, Teodora [4 ]
Mosteanu, Ofelia [4 ]
Mocan, Lucian [1 ,5 ]
Zdrehus, Claudiu [5 ]
机构：
[1] Octavian Fodor Gastroenterol Inst, Dept Nanomed, Cluj Napoca, Romania
[2] Iuliu Hatieganu Univ Med & Pharm, Dept Physiol, Cluj Napoca, Romania
[3] Univ Agr Sci & Vet Med, Fac Vet Med, Dept Pathol, Cluj Napoca, Romania
[4] Iuliu Hatieganu Univ Med & Pharm, Gastroenterol Dept 3, Cluj Napoca, Romania
[5] Iuliu Hatieganu Univ Med & Pharm, Surg Clin 3, Cluj Napoca, Romania
来源：
STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA | 2018年 / 63卷 / 03期
关键词：
gold nanoparticles; functionalization; MUC-1; peptide; SERUM-ALBUMIN; DELIVERY; CITRATE;
D O I：
10.24193/subbchem.2018.3.10
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Gold nanoparticles have been functionalized with the biologically active MUC-1 peptide conjugated to KLH and the obtained bionanostructure was characterized using an array of techniques such as: UV-Vis and ATR-FT-IR spectroscopy, dynamic light scattering (DLS) and atomic force microscopy (AFM). A 54 nm monodisperse bio-nanostructure with high aqueous stability was obtained.
引用
收藏
页码：129 / 135
页数：7
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