Multidisciplinary Code Shock Team in Cardiogenic Shock: A Canadian Centre Experience

被引:62
作者
Lee, Felicity [1 ]
Hutson, Jordan H. [1 ]
Boodhwani, Munir [2 ]
Mcdonald, Bernard [3 ]
So, Derek [1 ]
De Roock, Sophie [1 ]
Rubens, Fraser [2 ]
Stadnick, Ellamae [1 ]
Ruel, Marc [2 ]
Le May, Michel [1 ]
Labinaz, Marino [1 ]
Chien, Kevin [1 ]
Garuba, Habibat A. [1 ]
Mielniczuk, Lisa M. [1 ]
Chih, Sharon [1 ,4 ]
机构
[1] Univ Ottawa, Heart Inst, Div Cardiol, Ottawa, ON, Canada
[2] Univ Ottawa, Heart Inst, Div Cardiac Surg, Ottawa, ON, Canada
[3] Univ Ottawa, Heart Inst, Div Cardiac Anesthesiol, Ottawa, ON, Canada
[4] Univ Ottawa, Heart Inst, 40 Ruskin St, Ottawa, ON K1Y 4W7, Canada
关键词
ACUTE MYOCARDIAL-INFARCTION; MECHANICAL CIRCULATORY SUPPORT; VENTRICULAR ASSIST DEVICE; OUTCOMES; TRENDS; REVASCULARIZATION; MORTALITY; IMPELLA; CARE;
D O I
10.1016/j.cjco.2020.03.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Cardiogenic shock (CS) is associated with high mortality. We report on a "Shock Team" approach of combined interdisciplinary expertise for decision making, expedited assessment, and treatment. Methods: We reviewed 100 patients admitted in CS over 52 months. Patients managed under a Code Shock Team protocol (n = 64, treatment) from 2016 to 2019 were compared with standard care (n = 36, control) from 2015 to 2016. The cohort was predominantly male (78% treatment, 67% control) with a median age of 55 years (interquartile range [IQR], 43-64) for treatment vs 64 years (IQR, 48-69) for control (P = 0.01). New heart failure was more common in the treatment group: 61% vs 36%, P = 0.02. Acute myocardial infarction comprised 13% of patients in CS. There were no significant differences between treatment and control in markers of clinical acuity, including median left ventricular ejection fraction (18% vs 20%), prevalence ofmoderate-severe right ventricular dysfunction (64% vs 56%), median peak serum lactate (5.3 vs 4.7 mmol/L), acute kidney injury (70% vs 75%), or acute liver injury (50% vs 31%). Inotropes, dialysis, and invasive ventilation were required in 92%, 33%, and 66% of patients, respectively. Temporary mechanical circulatory support was used in 45% of treatment and 28% of control patients (P = 0.08). There were no significant differences in median hospital length of stay (17.5 days), 30-day survival (71%), or survival to hospital discharge (66%). Over 240 days (IQR, 14,847) of median follow-up, survival was 67% for treatment vs 42% for control (hazard ratio, 0.53; 95% confidence interval, 0.28-0.99; P = 0.03).Conclusion: A multidisciplinary Code Shock Team approach for CS is feasible and may be associated with improved long-term survival.
引用
收藏
页码:249 / 257
页数:9
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