Relationship between fatty acid intake and chronic neck/shoulder/upper limb pain without elevated CRP in a Japanese population: a cross-sectional analysis of the Shika study

被引：4

作者：

Asai, Atsushi ^{[1
]}

Suzuki, Fumihiko ^{[2
,3
]}

Tsujiguchi, Hiromasa ^{[1
,2
]}

Hara, Akinori ^{[1
,2
,4
]}

Miyagi, Sakae ^{[5
]}

Kannon, Takayuki ^{[4
,6
]}

Suzuki, Keita ^{[2
]}

Nakamura, Masaharu ^{[2
]}

Shimizu, Yukari ^{[7
]}

Nguyen, Thao Thi Thu ^{[8
]}

Pham, Kim Oanh

Kasahara, Tomoko ^{[1
]}

Nakai, Shingo ^{[1
]}

Hayashi, Koichiro ^{[1
]}

Shibata, Aki ^{[2
]}

Amatsu, Takashi ^{[1
]}

Konoshita, Tadashi ^{[9
]}

Kambayashi, Yasuhiro ^{[10
]}

Tsuboi, Hirohito ^{[11
]}

Tajima, Atsushi ^{[4
]}

Nakamura, Hiroyuki ^{[1
,2
,4
]}

机构：

[1] Kanazawa Univ, Grad Sch Med Sci, Dept Hyg & Publ Hlth, 13-1 Takaramachi, Kanazawa, Ishikawa 9208640, Japan

[2] Kanazawa Univ, Inst Med Pharmaceut & Hlth Sci, Dept Hyg & Publ Hlth, Fac Med, Kanazawa, Ishikawa 9208640, Japan

[3] Ohu Univ Hosp, Community Med Support Dent, Koriyama, Fukushima 9638611, Japan

[4] Kanazawa Univ, Adv Prevent Med Sci Res Ctr, 1-13 Takaramachi, Kanazawa, Ishikawa 9208640, Japan

[5] Kanazawa Univ, Innovat Clin Res Ctr, 13-1 Takaramachi, Kanazawa, Ishikawa 9208641, Japan

[6] Kanazawa Univ, Grad Sch Adv Prevent Med Sci, Dept Bioinformat & Genom, 13-1 Takaramachi, Kanazawa, Ishikawa 9208640, Japan

[7] Komatsu Univ, Dept Nursing, Fac Hlth Sci, 14-1 Mukaimotorimachi, Komatsu, Ishikawa 9230961, Japan

[8] Haiphong Univ Med & Pharm, Fac Publ Hlth, Hai Phong 180000, Vietnam

[9] Univ Fukui, Dept Internal Med 3, Fac Med Sci, 23-3 Matsuoka Shimoaizuki,Eiheiji Cho, Fukui 9101193, Japan

[10] Okayama Univ Sci, Dept Publ Hlth, Fac Vet Med, 1-3 Ikoinooka, Imabari, Ehime 7948555, Japan

[11] Kanazawa Univ, Inst Med Pharmaceut & Hlth Sci, 1 Kakuma Machi, Kanazawa, Ishikawa 9201192, Japan

来源：

JOURNAL OF NUTRITIONAL SCIENCE | 2022年 / 11卷

基金：

日本学术振兴会;

关键词：

Chronic pain; C-reactive protein; Cross-sectional study; Fatty acids; Logistic model; DIET HISTORY QUESTIONNAIRES; C-REACTIVE PROTEIN; ASSOCIATION; PREVALENCE; MECHANISMS; OBESITY;

D O I：

10.1017/jns.2022.37

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Although chronic pain (CP) is classified as inflammatory or non-inflammatory, the involvement of fatty acid intake in this process has not yet been examined in detail. Therefore, the present study investigated whether the relationship between CP and fatty acid intake differs between high and low C-reactive protein (CRP) levels in middle-aged and elderly individuals in the Shika study. One-thousand and seven males and 1216 females with mean ages of 68.78 and 69.65 years, respectively, participated in the present study. CRP was quantified by blood sampling from participants who responded to a CP questionnaire. The brief-type self-administered diet history questionnaire (BDHQ) was used to assess fatty acid intake. Interactions were observed between CP and CRP on monounsaturated fatty acids (MUFA) and eicosadienoic acid in a two-way analysis of covariance adjusted for sex, age, lack of exercise, lack of sleep, current smoking and drinking status, and BMI. MUFA (OR 1.359) and eicosadienoic acid (OR 1.072) were identified as significant independent variables for CP in a multiple logistic regression analysis, but only in the low CRP group. Only a high intake of MUFA and eicosadienoic acid was associated with chronic neck/shoulder/upper limb pain without elevated CRP. In psychogenic and neuropathic pain without elevated CRP, an increased intake of MUFA and eicosadienoic acid, a family member of n-6 fatty acids, appears to affect CP. Further longitudinal studies are needed to elucidate this relationship.

引用

页数：8

共 35 条

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