Functions of mammalian spinal interneurons during movement

被引:34
作者
Fetz, EE [1 ]
Perlmutter, SI [1 ]
Prut, Y [1 ]
机构
[1] Univ Washington, Dept Physiol & Biophys, Seattle, WA 98195 USA
关键词
D O I
10.1016/S0959-4388(00)00160-4
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The major recent advances in understanding the role of spinal neurons in generating movement include new information about the modulation of classic reflex;pathways during fictive locomotion and in response to pharmacological probes. The possibility of understanding movements in terms of spinal representations of a basic set of movement primitives has been extended by the analysis of normal reflexes. Recordings of the activity of cervical interneurons in behaving monkeys has elucidated their contribution to generating voluntary movement and revealed their involvement in movement preparation.
引用
收藏
页码:699 / 707
页数:9
相关论文
共 55 条
[1]  
Aggelopoulos NC, 1996, J NEUROSCI, V16, P723
[2]  
Alstermark, 1999, Acta Physiol Scand, V167, pA12
[3]   Disynaptic pyramidal excitation in forelimb motoneurons mediated via C3-C4 propriospinal neurons in the Macaca fuscata [J].
Alstermark, B ;
Isa, T ;
Ohki, Y ;
Saito, Y .
JOURNAL OF NEUROPHYSIOLOGY, 1999, 82 (06) :3580-3585
[4]   Group I extensor afferents evoke disynaptic EPSPs in cat hindlimb extensor motorneurones during fictive locomotion [J].
Angel, MJ ;
Guertin, P ;
Jimenez, I ;
McCrea, DA .
JOURNAL OF PHYSIOLOGY-LONDON, 1996, 494 (03) :851-861
[5]  
Baldissera F, 1981, HDB PHYSL 1 1, VII, P509, DOI DOI 10.1002/CPHY.CP010212
[6]   Tapping into spinal circuits to restore motor function [J].
Barbeau, H ;
McCrea, DA ;
O'Donovan, MJ ;
Rossignol, S ;
Grill, WM ;
Lemay, MA .
BRAIN RESEARCH REVIEWS, 1999, 30 (01) :27-51
[7]   A large-scale model of some spinal reflex circuits [J].
Bashor, DP .
BIOLOGICAL CYBERNETICS, 1998, 78 (02) :147-157
[8]   MODULAR ORGANIZATION OF MOTOR BEHAVIOR IN THE FROGS SPINAL-CORD [J].
BIZZI, E ;
GISZTER, SF ;
LOEB, E ;
MUSSAIVALDI, FA ;
SALTIEL, P .
TRENDS IN NEUROSCIENCES, 1995, 18 (10) :442-446
[9]   Mental simulation of an action modulates the excitability of spinal reflex pathways in man [J].
Bonnet, M ;
Decety, J ;
Jeannerod, M ;
Requin, J .
COGNITIVE BRAIN RESEARCH, 1997, 5 (03) :221-228
[10]   The use of state-dependent modulation of spinal reflexes as a tool to investigate the organization of spinal interneurons [J].
Burke, RE .
EXPERIMENTAL BRAIN RESEARCH, 1999, 128 (03) :263-277