Actin-binding channels

被引：7
|
作者：
Noda, Yumi [1 ,2 ]
Sasaki, Sei [1 ]
机构：
[1] Tokyo Med & Dent Univ, Dept Nephrol, Grad Sch Med, Bunkyo Ku, Tokyo, Japan
[2] Tokyo Med & Dent Univ, COE Program Brain Integrat & Its Disorders, Grad Sch Med, Bunkyo Ku, Tokyo, Japan
来源：
ADVANCES IN VASOPRESSIN AND OXYTOCIN: FROM GENES TO BEHAVIOUR TO DISEASE | 2008年 / 170卷
关键词：
actin remodelling; membrane trafficking; aquaporin;
D O I：
10.1016/S0079-6123(08)00442-1
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Channel proteins play essential roles in physiology including ion and volume homeostasis and signal transduction and in pathophysiology of many human diseases. Recently, the importance of the actin cytoskeleton in the channel protein regulation has been highlighted. The actin cytoskeleton and its reorganization have been reported to be required for the regulation of both channel activity and its intracellular trafficking. Furthermore, there are increasing evidences showing the direct interactions of channel to actin. This review focuses on actin-binding channel proteins and the role of the actin interaction in the channel protein regulation.
引用
收藏
页码：551 / 557
页数：7
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