Adrenaline in the treatment of anaphylaxis: what is the evidence?

被引:166
作者
McLean-Tooke, APC [1 ]
Bethune, CA [1 ]
Fay, AC [1 ]
Spickett, GP [1 ]
机构
[1] Royal Victoria Infirm, Reg Dept Immunol & Allergy, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
来源
BMJ-BRITISH MEDICAL JOURNAL | 2003年 / 327卷 / 7427期
关键词
D O I
10.1136/bmj.327.7427.1332
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Adrenaline (epinephrine) is the recommended first line treatment for patients with anaphylaxis. This review discusses the safety and efficacy of adrenaline in the treatment of anaphylaxis in the light of currently available evidence. A pragmatic approach to use of adrenaline auto-injectors is suggested.
引用
收藏
页码:1332 / 1335
页数:4
相关论文
共 25 条
[1]  
*AM ASS ALL ASTHM, MED RES POS STAT 26
[2]  
[Anonymous], 2003, Drug Ther Bull, V41, P21
[3]  
Brown AFT, 1998, J ACCID EMERG MED, V15, P89
[4]   The role of epinephrine in the treatment of anaphylaxis [J].
Ellis, AK ;
Day, JH .
CURRENT ALLERGY AND ASTHMA REPORTS, 2003, 3 (01) :11-14
[5]   Epinephrine absorption in adults: Intramuscular versus subcutaneous injection [J].
Estelle, F ;
Simons, R ;
Gu, XC ;
Simons, KJ .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 108 (05) :871-873
[6]  
FISCHER M, 1995, BMJ-BRIT MED J, V311, P731
[7]   First aid anaphylaxis management in children who were prescribed an epinephrine autoinjector device (EpiPen) [J].
Gold, MS ;
Sainsbury, R .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 106 (01) :171-176
[8]   Insect sting-inflicted systemic reactions: Attitudes of patients with insect venom allergy regarding after-sting behavior and proper administration of epinephrine [J].
Goldberg, A ;
Confino-Cohen, R .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 106 (06) :1184-1189
[9]   Lesson of the week - Adrenaline given outside the context of life threatening allergic reactions [J].
Johnston, SL ;
Unsworth, J ;
Gompels, MM .
BRITISH MEDICAL JOURNAL, 2003, 326 (7389) :589-590
[10]   UNDERREPORTING OF ANAPHYLAXIS IN A COMMUNITY EMERGENCY ROOM [J].
KLEIN, JS ;
YOCUM, MW .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1995, 95 (02) :637-638