Development of an Anthropomorphic Breast Phantom for Combined PET, B-Mode Ultrasound and Elastographic Imaging

被引：27

作者：

Dang, Jun ^{[1
]}

Frisch, Benjamin ^{[2
]}

Lasaygues, Philippe ^{[3
]}

Zhang, Dachun ^{[4
]}

Tavernier, Stefaan ^{[1
]}

Felix, Nicolas

Lecoq, Paul ^{[2
]}

Auffray, Etiennette ^{[2
]}

Varela, Joao ^{[5
]}

Mensah, Serge ^{[3
]}

Wan, Mingxi ^{[4
]}

机构：

[1] Vrije Univ Brussel, B-1050 Brussels, Belgium

[2] CERN, CH-1211 Geneva 23, Switzerland

[3] Natl Ctr French Sci Res CNRS LMA, F-13402 Marseille 20, France

[4] Xi An Jiao Tong Univ, Xian 710049, Shaanxi, Peoples R China

[5] Lab Instrumentacao & Fis Expt Particulas LIP, P-1000149 Lisbon, Portugal

来源：

IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 2011年 / 58卷 / 03期

关键词：

Breast; elastography; PET; ultrasound; MUTUAL-INFORMATION; REGISTRATION; OPTIMIZATION; MAXIMIZATION; MAMMOGRAPHY; SENSITIVITY;

D O I：

10.1109/TNS.2011.2105279

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Combining the advantages of different imaging modalities leads to improved clinical results. For example, ultrasound provides good real-time structural information without any radiation and PET provides sensitive functional information. For the ongoing ClearPEM-Sonic project combining ultrasound and PET for breast imaging, we developed a dual-modality PET/Ultrasound (US) phantom. The phantom reproduces the acoustic and elastic properties of human breast tissue and allows labeling the different tissues in the phantom with different concentrations of FDG. The phantom was imaged with a whole-body PET/CT and with the Supersonic Imagine Aixplorer system. This system allows both B-mode US and shear wave elastographic imaging. US elastography is a new imaging method for displaying the tissue elasticity distribution. It was shown to be useful in breast imaging. We also tested the phantom with static elastography. A 6D magnetic positioning system allows fusing the images obtained with the two modalities. ClearPEM-Sonic is a project of the Crystal Clear Collaboration and the European Centre for Research on Medical Imaging (CERIMED).

引用

页码：660 / 667

页数：8

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