Clinical studies using stem cells for treatment of retinal diseases: state of the art

被引:9
作者
Cotrim, Carina Costa [1 ]
Jorge, Rodrigo [1 ]
de Oliveira, Maria Carolina [2 ]
Pieroni, Fabiano [2 ]
Vieira Messias, Andre M. [1 ]
Siqueira, Rubens Camargo [1 ,3 ]
机构
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Ophthalmol Otorhinolaryngol & Head & Neck Su, Ribeirao Preto, SP, Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Internal Med, Ribeirao Preto, SP, Brazil
[3] Univ Estadual Sao Jose do Rio Preto, Fac Med, Sao Jose Do Rio Preto, SP, Brazil
关键词
Stem cells; Retinal progenitor cells; Embryonic stem cells; Induced pluripotent stem cells; Bone marrow-derived stem cells; INTRAVITREAL USE; MACULAR EDEMA; THERAPY; LINES; DIFFERENTIATION; GENERATION;
D O I
10.5935/0004-2749.20200037
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Degenerative retinal diseases such as retinitis pigmentosa, Stargardt's macular dystrophy, and age-related macular degeneration are characterized by irreversible loss of vision due to director indirect photoreceptor damage. No effective treatments exist, but stem cell studies have shown promising results. Our aim with this review was to describe the types of stem cells that are under study, their effects, and the main clinical trials involving them.
引用
收藏
页码:160 / 167
页数:8
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