Toward Clinically Applicable 3-Dimensional Tooth Segmentation via Deep Learning

被引:36
作者
Hao, J. [1 ,2 ,3 ,4 ]
Liao, W. [1 ,2 ,3 ]
Zhang, Y. L. [1 ,2 ,3 ]
Peng, J. [5 ]
Zhao, Z. [5 ]
Chen, Z. [5 ]
Zhou, B. W. [6 ]
Feng, Y. [6 ]
Fang, B. [7 ]
Liu, Z. Z. [8 ]
Zhao, Z. H. [1 ,2 ,3 ]
机构
[1] Sichuan Univ, State Key Lab Oral Dis, Chengdu, Peoples R China
[2] Sichuan Univ, Natl Clin Res Ctr Oral Dis, Chengdu, Peoples R China
[3] Sichuan Univ, West China Hosp Stomatol, Chengdu, Peoples R China
[4] Harvard Univ, Harvard Sch Dent Med, Boston, MA 02115 USA
[5] DeepAlign Tech Inc, Ningbo, Peoples R China
[6] Angel Align Inc, Angelalign Res Inst, Shanghai, Peoples R China
[7] Shanghai Jiao Tong Univ, Shanghai Res Inst Stomatol, Natl Clin Res Ctr Stomatol, Peoples Hosp 9, Shanghai, Peoples R China
[8] Zhejiang Univ, Zhejiang Univ Univ Illinois Urbana Champaign Inst, 718 East Haizhou Rd, Haining 314400, Zhejiang, Peoples R China
关键词
intraoral scan; machine learning; artificial intelligence; medical imaging; neural networks; digital dentistry;
D O I
10.1177/00220345211040459
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Digital dentistry plays a pivotal role in dental health care. A critical step in many digital dental systems is to accurately delineate individual teeth and the gingiva in the 3-dimension intraoral scanned mesh data. However, previous state-of-the-art methods are either time-consuming or error prone, hence hindering their clinical applicability. This article presents an accurate, efficient, and fully automated deep learning model trained on a data set of 4,000 intraoral scanned data annotated by experienced human experts. On a holdout data set of 200 scans, our model achieves a per-face accuracy, average-area accuracy, and area under the receiver operating characteristic curve of 96.94%, 98.26%, and 0.9991, respectively, significantly outperforming the state-of-the-art baselines. In addition, our model takes only about 24 s to generate segmentation outputs, as opposed to >5 min by the baseline and 15 min by human experts. A clinical performance test of 500 patients with malocclusion and/or abnormal teeth shows that 96.9% of the segmentations are satisfactory for clinical applications, 2.9% automatically trigger alarms for human improvement, and only 0.2% of them need rework. Our research demonstrates the potential for deep learning to improve the efficacy and efficiency of dental treatment and digital dentistry.
引用
收藏
页码:304 / 311
页数:8
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