Prevalence and European comparison of dementia in a ≥75-year-old composite population in Spain

被引：24

作者：

Virues-Ortega, J. ^{[1
]}

de Pedro-Cuesta, J. ^{[1
]}

Vega, S. ^{[2
]}

Seijo-Martinez, M. ^{[3
]}

Saz, P. ^{[4
]}

Rodriguez, F. ^{[5
]}

Rodriguez-Laso, A. ^{[6
]}

Rene, R. ^{[7
]}

de las Heras, S. P. ^{[8
]}

Mateos, R. ^{[9
]}

Martinez-Martin, P. ^{[1
]}

Mahillo-Fernandez, I. ^{[1
]}

Lopez-Pousa, S. ^{[10
]}

Lobo, A. ^{[4
]}

Regla, J. L. ^{[10
]}

Gascon, J. ^{[7
]}

Garcia, F. J. ^{[11
]}

Fernandez-Martinez, M. ^{[12
]}

Boix, R.

Bermejo-Pareja, F. ^{[13
,14
]}

Bergareche, A. ^{[15
]}

Sanchez-Sanchez, F. ^{[13
,14
]}

de Arce, A. ^{[15
]}

del Barrio, J. L. ^{[1
]}

机构：

[1] Inst Salud Carlos III, Ctr Nacl Epidemiol, Res Network Nerodegenerat Dis CIBERNED, Madrid 28029, Spain

[2] El Espinar Hlth Ctr, El Espinar, Segovia, Spain

[3] Salnes Hosp, Neurol Unit, Pontevedra, Spain

[4] Univ Zaragoza, Dept Med & Psychiat, Zaragoza, Spain

[5] Segovia Hosp, Neurol Unit, Segovia, Spain

[6] Madrid Reg Hlth Author, Madrid, Spain

[7] Bellvitge Univ Hosp, Dept Neurol, Dementia Diag & Treatment Unit, Barcelona, Spain

[8] Day Med Ctr, Llodio Hlth Ctr, Oroityu Getxo Vizcaya, Spain

[9] Univ Santiago de Compostela, Dept Psychiat, Santiago De Compostela, Spain

[10] Hosp Santa Caterina, Inst Assistencia Sanitaria, Dementia Unit, Salt, Spain

[11] Virgen del Valle Geriatr Hosp, Geriatr Unit, Toledo, Spain

[12] Cruces Hosp, Day Med Ctr, Neurol Serv, Oroityu Getxo Vizcaya, Spain

[13] 12 Octubre Univ Teaching Hosp, Dept Neurol, Madrid, Spain

[14] CIBERNED, Madrid, Spain

[15] Bidasoa Hondarribia Hosp, Dept Neurol, Guipuzcoa, Spain

来源：

ACTA NEUROLOGICA SCANDINAVICA | 2011年 / 123卷 / 05期

关键词：

dementia; Alzheimer's disease; vascular dementia; prevalence; Spain; TO-DOOR SURVEY; PARKINSONS-DISEASE; COGNITIVE IMPAIRMENT; LEWY BODIES; CONSENSUS; DEPRESSION; CRITERIA; SUBTYPES; OLDER; AGE;

D O I：

10.1111/j.1600-0404.2010.01398.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives - To estimate dementia prevalence in Spain. Materials and methods - Nine probabilistic and geographically defined samples participated. A screening design based on the MMSE was implemented. Positively screened individuals underwent clinical evaluation. The total number of cases in Spain was estimated. Prevalence was confronted to that of other European countries. Results - Five hundred and forty-six persons aged >= 75 participated, 49 had dementia (35 with Alzheimer's disease [AD], 10 with vascular dementia [VD], 4 other; 25 first diagnosed in the study). Age- and sex-adjusted prevalence and estimated nationwide cases were 7.5% (95% CI 5.4-9.7), 5.6 (95% CI 3.7-7.5) and 1.4 (95% CI 0.5-2.3), and 290,000 (95% CI 208,000-372,000), 214,000 (95% CI 141,000-288,000) and 54,000 (95% CI 20,000-88,000) for dementia, AD and VD, respectively. Conclusions - Dementia prevalence in Spain is comparable to other European populations, while a high number of undiagnosed cases live in the community. The potential impact of Mediterranean diet, hypertension control and decreasing vascular risk factors is discussed.

引用

页码：316 / 324

页数：9

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