An Enzyme Cascade Reaction for the Recovery of Hydroxytyrosol Dervatives from Olive Mill Wastewater

被引：3

作者：

Terholsen, Henrik ^{[1
]}

Kaur, Jasmin ^{[1
]}

Kaloudis, Nikolaos ^{[2
]}

Staudt, Amanda ^{[1
]}

Pavlidis, Ioannis, V ^{[2
]}

Bornscheuer, Uwe T. ^{[1
]}

机构：

[1] Univ Greifswald, Dept Biotechnol & Enzyme Catalysis, Felix Hausdorff Str 4, D-17487 Greifswald, Germany

[2] Univ Crete, Dept Chem, Voutes Univ Campus, Iraklion 70013, Greece

来源：

CHEMIE INGENIEUR TECHNIK | 2022年 / 94卷 / 11期

关键词：

Cascade reaction; Flow catalysis; Hydroxytyrosol; Olive mill wastewaters valorization; Promiscuous acyltransferase; BETA-GLUCOSIDASE; ANTIOXIDANTS; HYDROLYSIS;

D O I：

10.1002/cite.202200069

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

The valorization of olive mill wastewaters (OMWW), a by-product of the olive milling, is getting rising attention. Lipophilization of the main phenolic compound 3-hydroxytyrosol (HT) could facilitate its extraction. An immobilized variant of the promiscuous hydrolase/acyltransferase from Pyrobaculum calidifontis VA1 (PestE) was used to perform acetylation in water using ethyl acetate as acyl donor. PestE was used in a segmented flow setting to allow continuous operation. Additionally, HT precursors were made accessible by pretreatment with almond beta-glucosidase and the hydrolytic activity of PestE_I208A_L209F_N288A.

引用

页码：1860 / 1863

页数：4

共 50 条

[21] Triple Enzymatic Cascade Reaction to Produce Hydroxytyrosol Acetate from Olive Leaves Using Integrated Membrane Bioreactors
Mazzei, Rosalinda
Bazzarelli, Fabio
Terholsen, Henrik
Nardi, Monica
Piacentini, Emma
Procopio, Antonio
Bornscheuer, Uwe T.
Giorno, Lidietta
CHEMSUSCHEM, 2025, 18 (05)
[22] Hydroxytyrosol-rich olive mill wastewater extract protects brain cells in vitro and ex vivo
Schaffer, Sebastian
Podstawa, Maciej
Visioli, Francesco
Bogani, Paola
Mueller, Walter E.
Eckert, Gunter P.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 55 (13) : 5043 - 5049
[23] Potential use of hydroxytyrosol-rich extract from olive mill wastewater as a biological fungicide against Botrytis cinerea in tomato
Yangui, Thabet
Sayadi, Sami
Rhouma, Ali
Dhouib, Abdelhafidh
JOURNAL OF PEST SCIENCE, 2010, 83 (04) : 437 - 445
[24] Potential of hydroxytyrosol-rich composition from olive mill wastewater as a natural disinfectant and its effect on seeds vigour response
Yangui, Thabet
Dhouib, Abdelhafidh
Rhouma, Ali
Sayadi, Sami
FOOD CHEMISTRY, 2009, 117 (01) : 1 - 8
[25] Amine-modified mesoporous silica for quantitative adsorption and release of hydroxytyrosol and other phenolic compounds from olive mill wastewater
Yangui, Asma
Abderrabba, Manef
Sayari, Abdelhamid
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS, 2017, 70 : 111 - 118
[26] Potential use of hydroxytyrosol-rich extract from olive mill wastewater as a biological fungicide against Botrytis cinerea in tomato
Thabèt Yangui
Sami Sayadi
Ali Rhouma
Abdelhafidh Dhouib
Journal of Pest Science, 2010, 83 : 437 - 445
[27] Recovering Polyphenols in Aqueous Solutions from Olive Mill Wastewater and Olive Leaf for Biological Applications
Hernandez-Fernandez, Adrian
Garrido, Yolanda
Iniesta-Lopez, Eduardo
de los Rios, Antonia Perez
Quesada-Medina, Joaquin
Hernandez-Fernandez, Francisco Jose
PROCESSES, 2023, 11 (09)
[28] Valorization of an Underutilized Waste from Olive Oil Production by Recovery of Hydroxytyrosol
Squillaci, Giuseppe
Serino, Ismene
Errichiello, Sara
La Cara, Francesco
Morana, Alessandra
PROCESSES, 2022, 10 (10)
[29] Performance and modeling of continuous ion exchange processes for phenols recovery from olive mill wastewater
Victor-Ortega, M. D.
Ochando-Pulido, J. M.
Martinez-Ferez, A.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 2016, 100 : 242 - 251
[30] Valorization of antioxidants extracted from olive mill wastewater
Aissa, Imen
Kharrat, Nadia
Aloui, Fatma
Sellami, Mohamed
Bouaziz, Mohamed
Gargouri, Youssef
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2017, 64 (04) : 579 - 589

← 1 2 3 4 5 →