Synapse Type-Dependent Expression of Calcium-Permeable AMPA Receptors

被引：30

作者：

Lalanne, Txomin ^{[1
]}

Oyrer, Julia ^{[2
]}

Farrant, Mark ^{[3
]}

Sjostrom, P. Jesper ^{[4
]}

机构：

[1] Univ Basel, Dept Biomed, Inst Physiol, Basel, Switzerland

[2] Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Parkville, Vic, Australia

[3] UCL, Dept Neurosci Physiol & Pharmacol, London, England

[4] McGill Univ, Brain Repair & Integrat Neurosci Program, Montreal Gen Hosp,Hlth Ctr, Ctr Res Neurosci,Dept Neurol & Neurosurg,Res Inst, Montreal, PQ, Canada

来源：

FRONTIERS IN SYNAPTIC NEUROSCIENCE | 2018年 / 10卷

基金：

加拿大自然科学与工程研究理事会;

关键词：

AMPAR; NMDAR; neocortex; hippocampus; parvalbumin; somatostatin; interneuron; synapse-type-specific plasticity; IONOTROPIC GLUTAMATE RECEPTORS; LONG-TERM POTENTIATION; FAST-SPIKING INTERNEURONS; CA2+-PERMEABLE AMPA; SUBUNIT COMPOSITION; PYRAMIDAL CELLS; NMDA RECEPTORS; INWARD RECTIFICATION; TRANSMITTER RELEASE; HIPPOCAMPAL-NEURONS;

D O I：

10.3389/fnsyn.2018.00034

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Calcium-permeable (CP) AMPA-type glutamate receptors (AMPARs) are known to mediate synaptic plasticity in several different interneuron (IN) types. Recent evidence suggests that CP-AMPARs are synapse-specifically expressed at excitatory connections onto a subset of IN types in hippocampus and neocortex. For example, CP-AMPARs are found at connections from pyramidal cells (PCs) to basket cells (BCs), but not to Martinotti cells (MCs). This synapse type-specific expression of CP-AMPARs suggests that synaptic dynamics as well as learning rules are differentially implemented in local circuits and has important implications not just in health but also in disease states such as epilepsy.

引用

页数：8

共 103 条

[1] Synaptic computation [J].

Abbott, LF ;

Regehr, WG .

NATURE, 2004, 431 (7010) :796-803

[2] Differential Regulation of Evoked and Spontaneous Release by Presynaptic NMDA Receptors [J].

Abrahamsson, Therese ;

Chou, Christina You Chien ;

Li, Si Ying ;

Mancino, Adamo ;

Costa, Rui Ponte ;

Brock, Jennifer Anne ;

Nuro, Erin ;

Buchanan, Katherine Anne ;

Elgar, Dale ;

Blackman, Arne Vladimir ;

Tudor-Jones, Adam ;

Oyrer, Julia ;

Farmer, William Todd ;

Murai, Keith Kazuo ;

Sjostrom, Per Jesper .

NEURON, 2017, 96 (04) :839-+

[3] Diverse roles for ionotropic glutamate receptors on inhibitory interneurons in developing and adult brain [J].

Akguel, Guelcan ;

McBain, Chris J. .

JOURNAL OF PHYSIOLOGY-LONDON, 2016, 594 (19) :5471-5490

[4]

Angulo MC, 1997, J NEUROSCI, V17, P6685

[5] Efficient Ca2+ buffering in fast-spiking basket cells of rat hippocampus [J].

Aponte, Yexica ;

Bischofberger, Josef ;

Jonas, Peter .

JOURNAL OF PHYSIOLOGY-LONDON, 2008, 586 (08) :2061-2075

[6] Target-Dependent Feedforward Inhibition Mediated by Short-Term Synaptic Plasticity in the Cerebellum [J].

Bao, Jin ;

Reim, Kerstin ;

Sakaba, Takeshi .

JOURNAL OF NEUROSCIENCE, 2010, 30 (24) :8171-8179

[7]

Blackman Arne V, 2013, Front Synaptic Neurosci, V5, P11, DOI 10.3389/fnsyn.2013.00011

[8] INWARD RECTIFICATION OF BOTH AMPA AND KAINATE SUBTYPE GLUTAMATE RECEPTORS GENERATED BY POLYAMINE-MEDIATED ION-CHANNEL BLOCK [J].

BOWIE, D ;

MAYER, ML .

NEURON, 1995, 15 (02) :453-462

[9] Redefining the classification of AMPA-selective ionotropic glutamate receptors [J].

Bowie, Derek .

JOURNAL OF PHYSIOLOGY-LONDON, 2012, 590 (01) :49-61

[10] EARLY-ONSET EPILEPSY AND POSTNATAL LETHALITY ASSOCIATED WITH AN EDITING-DEFICIENT GLUR-B ALLELE IN MICE [J].

BRUSA, R ;

ZIMMERMANN, F ;

KOH, DS ;

FELDMEYER, D ;

GASS, P ;

SEEBURG, PH ;

SPRENGEL, R .

SCIENCE, 1995, 270 (5242) :1677-1680

← 1 2 3 4 5 6 7 8 9 10 →