Radical Vaginal Trachelectomy with Laparoscopic Pelvic Lymphadenectomy for Fertility Preservation in Young Women with Early-Stage Cervical Cancer

被引:7
作者
Bratila, Elvira [1 ,2 ]
Bratila, C. P. [1 ,3 ]
Coroleuca, C. B. [2 ]
机构
[1] Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, Bucharest, Romania
[2] Clin Emergency Hosp Sf Pantelimon, Dept Obstet & Gynecol, Sos Pantelimon 340-342, Bucharest, Romania
[3] Minimally Invas Surg Hosp Euroclin Regina Maria, Bucharest, Romania
关键词
Cervical cancer; Radical vaginal trachelectomy; Laparoscopic pelvic lymphadenectomy; Pregnancy; OBSTETRIC MANAGEMENT; HYSTERECTOMY; CARCINOMA; OUTCOMES; SURGERY;
D O I
10.1007/s12262-015-1351-3
中图分类号
R61 [外科手术学];
学科分类号
摘要
The primary objective of this study was to describe our experience with the conservative treatment of early-stage cervical cancer (stages IA1, IA2, and IB1) with radical vaginal trachelectomy (RVT) and laparoscopic pelvic lymphadenectomy. This retrospective observational case series included 36 patients with early cervical cancer. Radical trachelectomy and laparoscopic pelvic lymphadenectomy were performed as described by D. Dargent in 32 of these cases. Oncologic, reproductive, and obstetric outcomes were observed subsequently over a median period of 42 (24-96) weeks. A total of 32 RVTs were preformed with a mean operating time of 117 +/- 22.8 (77-167) minutes and an average blood loss of 486 mL (150-800 mL). All obtained resection margins were negative for cancer. Lymphovascular space invasion was noted in 11 (30.55 %) of the cases. No recurrences occurred during the study period. Seven (17.8 %) patients were able to become pregnant postoperatively, five of whom delivered healthy infants near term. Radical vaginal trachelectomy with laparoscopic pelvic lymphadenectomy appears to be a safe therapeutic option for fertility preservation in young women with early cervical cancer.
引用
收藏
页码:265 / 270
页数:6
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