Surgery and treatment with high-dose liposomal amphotericin B for eradication of craniofacial zygomycosis in a patient with Hodgkin's disease who had undergone allogeneic hematopoietic stem cell transplantation
被引:16
作者:
Barron, MA
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Univ Colorado, Hlth Sci Ctr, Denver, CO 80262 USAUniv Colorado, Hlth Sci Ctr, Denver, CO 80262 USA
Barron, MA
[1
]
Lay, M
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Univ Colorado, Hlth Sci Ctr, Denver, CO 80262 USAUniv Colorado, Hlth Sci Ctr, Denver, CO 80262 USA
Lay, M
[1
]
Madinger, NE
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Univ Colorado, Hlth Sci Ctr, Denver, CO 80262 USAUniv Colorado, Hlth Sci Ctr, Denver, CO 80262 USA
Madinger, NE
[1
]
机构:
[1] Univ Colorado, Hlth Sci Ctr, Denver, CO 80262 USA
This case report describes craniofacial zygomycosis in a 24-year-old male with Hodgkin's disease who underwent chemotherapy and autologous hematopoietic stem cell transplantation, followed by a nonmyeloablative allogeneic transplant. Empirical therapy with itraconazole and amoxicillin-clavulanate failed to resolve the infection. Postdiagnosis, surgery and treatment with high-dose liposomal amphotericin B eradicated the disease.