Activating Autophagy to Prevent Doxorubicin Cardiomyopathy The Timing Matters

被引：8
作者：
Asnani, Aarti [1 ,2 ]
机构：
[1] Beth Israel Deaconess Med Ctr, Dept Med, Div Cardiovasc Med, Boston, MA 02215 USA
[2] Harvard Med Sch, 3 Blackfan Cir,CLS-911, Boston, MA 02215 USA
来源：
CIRCULATION RESEARCH | 2021年 / 129卷 / 08期
基金：
美国国家卫生研究院;
关键词：
Editorials; autophagy; cardiomyopathies; doxorubicin; HEART-FAILURE; CARDIOTOXICITY; DEXRAZOXANE;
D O I：
10.1161/CIRCRESAHA.121.320063
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：801 / 803
页数：3
相关论文
共 16 条
  • [1] Early Detection of Anthracycline Cardiotoxicity and Improvement With Heart Failure Therapy
    Cardinale, Daniela
    Colombo, Alessandro
    Bacchiani, Giulia
    Tedeschi, Ines
    Meroni, Carlo A.
    Veglia, Fabrizio
    Civelli, Maurizio
    Lamantia, Giuseppina
    Colombo, Nicola
    Curigliano, Giuseppe
    Fiorentini, Cesare
    Cipolla, Carlo M.
    [J]. CIRCULATION, 2015, 131 (22) : 1981 - 1988
  • [2] Ferroptosis as a target for protection against cardiomyopathy
    Fang, Xuexian
    Wang, Hao
    Han, Dan
    Xie, Enjun
    Yang, Xiang
    Wei, Jiayu
    Gu, Shanshan
    Gao, Feng
    Zhu, Nali
    Yin, Xiangju
    Cheng, Qi
    Zhang, Pan
    Dai, Wei
    Chen, Jinghai
    Yang, Fuquan
    Yang, Huang-Tian
    Linkermann, Andreas
    Gu, Wei
    Min, Junxia
    Wang, Fudi
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (07) : 2672 - 2680
  • [3] DOXORUBICIN CARDIOTOXICITY - SERIAL ENDOMYOCARDIAL BIOPSIES AND SYSTOLIC-TIME INTERVALS
    FRIEDMAN, MA
    BOZDECH, MJ
    BILLINGHAM, ME
    RIDER, AK
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1978, 240 (15): : 1603 - 1606
  • [4] Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation
    Ichikawa, Yoshihiko
    Ghanefar, Mohsen
    Bayeva, Marina
    Wu, Rongxue
    Khechaduri, Arineh
    Prasad, Sathyamangla V. Naga
    Mutharasan, R. Kannan
    Naik, Tejaswitha Jairaj
    Ardehali, Hossein
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (02) : 617 - 630
  • [5] LEFRAK EA, 1973, CANCER-AM CANCER SOC, V32, P302, DOI 10.1002/1097-0142(197308)32:2<302::AID-CNCR2820320205>3.0.CO
  • [6] 2-2
  • [7] Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome Acidification
    Li, Dan L.
    Wang, Zhao V.
    Ding, Guanqiao
    Tan, Wei
    Luo, Xiang
    Criollo, Alfredo
    Xie, Min
    Jiang, Nan
    May, Herman
    Kyrychenko, Viktoriia
    Schneider, Jay W.
    Gillette, Thomas G.
    Hill, Joseph A.
    [J]. CIRCULATION, 2016, 133 (17) : 1668 - 1687
  • [8] Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth
    Li, Mingchuan
    Sala, Valentina
    De Santis, Maria Chiara
    Cimino, James
    Cappello, Paola
    Pianca, Nicola
    Di Bona, Anna
    Margaria, Jean Piero
    Martini, Miriam
    Lazzarini, Edoardo
    Pirozzi, Flora
    Rossi, Luca
    Franco, Irene
    Bornbaum, Julia
    Heger, Jacqueline
    Rohrbach, Susanne
    Perino, Alessia
    Tocchetti, Carlo G.
    Lima, Braulio H. F.
    Teixeira, Mauro M.
    Porporato, Paolo E.
    Schulz, Rainer
    Angelini, Annalisa
    Sandri, Marco
    Ameri, Pietro
    Sciarretta, Sebastiano
    Lima-Junior, Roberto Cesar P.
    Mongillo, Marco
    Zaglia, Tania
    Morello, Fulvio
    Novelli, Francesco
    Hirsch, Emilio
    Ghigo, Alessandra
    [J]. CIRCULATION, 2018, 138 (07) : 696 - 711
  • [9] ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation
    Park, Eunhee
    Chung, Su Wol
    [J]. CELL DEATH & DISEASE, 2019, 10 (11)
  • [10] Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer
    Swain, SM
    Whaley, FS
    Gerber, MC
    Weisberg, S
    York, M
    Spicer, D
    Jones, SE
    Wadler, S
    Desai, A
    Vogel, C
    Speyer, J
    Mittelman, A
    Reddy, S
    Pendergrass, K
    VelezGarcia, E
    Ewer, MS
    Bianchine, JR
    Gams, RA
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (04) : 1318 - 1332
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