Effect of surfactants on the production of ergot-alkaloids by immobilized mycelia of Claviceps paspali

被引：2

作者：

Matosic, S ^{[1
]}

Mehak, M ^{[1
]}

Ercegovic, L ^{[1
]}

Brajkovic, N ^{[1
]}

Suskovic, J ^{[1
]}

机构：

[1] Univ Zagreb, Dept Biochem Engn, Fac Food Technol & Biotechnol, Zagreb 41000, Croatia

来源：

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY | 1998年 / 14卷 / 03期

关键词：

Claviceps; ergot alkaloids; immobilization; surfactant;

D O I：

10.1023/A:1008837916873

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In a semicontinuous process immobilized Claviceps paspali mycelia produced alkaloids over a period of 60 days (six reincubations). By addition of the surfactant Pluronik, a polyethoxypolypropoxy polymer, a considerable increase in alkaloid biosynthesis occurred. The maximum product concentration achieved was 8.35 g l(-1), and the overall productivity was 5.80 mg l(-1) h(-1), which is half the productivity of the batch process. Maximum process productivity for a single reincubation (12.3 mg l(-1) h(-1)) was almost equal to the batch process productivity.

引用

页码：447 / 450

页数：4

共 23 条

[1] PRODUCTION OF A NEW LYSERGIC ACID DERIVATIVE IN SUBMERGED CULTURE BY A STRAIN OF CLAVICEPS PASPALI STEVENS AND HALL
ARCAMONE, F
CHAIN, EB
VERO, L
FERRETTI, A
MINGHETTI, A
TONOLO, A
PENNELLA, P
[J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1961, 155 (958): : 26 - +
[2] LARGE-SCALE PRODUCTION OF CLAVINE ALKALOIDS BY CLAVICEPS-FUSIFORMIS
BANKS, GT
MANTLE, PG
SZCZYRBAK, CA
[J]. JOURNAL OF GENERAL MICROBIOLOGY, 1974, 82 (JUN): : 345 - 361
[3] EFFECT OF TWEEN SERIES SURFACTANTS ON ALKALOID PRODUCTION BY SUBMERGED CULTURES OF CLAVICEPS SPECIES
DESAI, JD
PATEL, HC
DESAI, AJ
[J]. JOURNAL OF FERMENTATION TECHNOLOGY, 1986, 64 (06): : 499 - 501
[4] LONG-TERM PRODUCTION OF ERGOT PEPTIDES BY IMMOBILIZED CLAVICEPS-PURPUREA IN SEMICONTINUOUS AND CONTINUOUS-CULTURE
DIERKES, W
LOHMEYER, M
REHM, HJ
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1993, 59 (07) : 2029 - 2033
[5] Gilmanov V, 1996, J APPL BACTERIOL, V81, P678
[6] Tween 80 effect on bacteriocin synthesis by Lactococcus lactis subsp cremoris J46
Huot, E
BarrenaGonzalez, C
Petitdemange, H
[J]. LETTERS IN APPLIED MICROBIOLOGY, 1996, 22 (04) : 307 - 310
[7] ALKALOID PRODUCTION BY IMMOBILIZED MYCELIA OF CLAVICEPS-PURPUREA
KOPP, B
REHM, HJ
[J]. EUROPEAN JOURNAL OF APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1983, 18 (05): : 257 - 263
[8] KOPP B, 1984, P 3 EUR C BIOT WEINH, V1, P281
[9] KREN V, 1987, APPL MICROBIOL BIOT, V26, P219
[10] MATOSIC S, 1984, Acta Botanica Croatica, V43, P59

← 1 2 3 →