Review on practical photoacoustic microscopy

被引：244

作者：

Jeon, Seungwan ^{[1
]}

Kim, Jongbeom ^{[1
]}

Lee, Donghyun ^{[1
]}

Baik, Jin Woo ^{[1
]}

Kim, Chulhong ^{[1
]}

机构：

[1] Pohang Univ Sci & Technol POSTECH, Dept Creat IT Engn, Pohang 37673, South Korea

来源：

PHOTOACOUSTICS | 2019年 / 15卷

基金：

新加坡国家研究基金会;

关键词：

Optoacoustics; Resolution; SNR; Fast scanning; FROZEN-SECTION ANALYSIS; IN-VIVO; HIGH-RESOLUTION; ULTRASOUND SENSOR; TOMOGRAPHY; COHERENCE; NEOVASCULARIZATION; INTERFEROMETER; CANCER; INDEX;

D O I：

10.1016/j.pacs.2019.100141

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Photoacoustic imaging (PAI) has many interesting advantages, such as deep imaging depth, high image resolution, and high contrast to intrinsic and extrinsic chromophores, enabling morphological, functional, and molecular imaging of living subjects. Photoacoustic microscopy (PAM) is one form of the PAI inheriting its characteristics and is useful in both preclinical and clinical research. Over the years, PAM systems have been evolved in several forms and each form has its relative advantages and disadvantages. Thus, to maximize the benefits of PAM for a specific application, it is important to configure the PAM system optimally by targeting a specific application. In this review, we provide practical methods for implementing a PAM system to improve the resolution, signal-to-noise ratio (SNR), and imaging speed. In addition, we review the preclinical and the clinical applications of PAM and discuss the current challenges and the scope for future developments.

引用

页数：16

共 138 条

[1] Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy [J].