Recent progress in sepsis epidemiology - have we learned enough?

被引：7

作者：

Gerlach, H ^{[1
]}

Keh, D

机构：

[1] Vivantes Klinikum Neukoelln, Dept Anesthesiol & Crit Care Med, Berlin, Germany

[2] Charite Virchow Klinikum, Dept Anesthesiol & Crit Care Med, Berlin, Germany

来源：

CRITICAL CARE | 2003年 / 7卷 / 05期

关键词：

definition; epidemiology; organ failure; quality improvement; sepsis;

D O I：

10.1186/cc2175

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The encouraging results of recent clinical trials on therapy of severe sepsis and septic shock are paralleled by ongoing studies on the epidemiology of sepsis and infection in intensive care unit patients all over the world. The development of network-based systems for assessing morbidity and mortality in intensive care unit patients has contributed to a significant improvement in quality of care. Data from the SOAP (Sepsis Occurrence in the Acutely Ill Patient) study demonstrate that the treatment of septic patients varies widely, and that even those strategies that have been evaluated are not yet implemented in routine practice. Hence, activities on surveillance and education still merit further attention.

引用

页码：333 / 334

页数：2

共 12 条

[1] Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study [J].

Alberti, C ;

Brun-Buisson, C ;

Burchardi, H ;

Martin, C ;

Goodman, S ;

Artigas, A ;

Sicignano, A ;

Palazzo, M ;

Moreno, R ;

Boulmé, R ;

Lepage, E ;

Le Gall, JR .

INTENSIVE CARE MEDICINE, 2002, 28 (02) :108-121

[2] Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care [J].

Angus, DC ;

Linde-Zwirble, WT ;

Lidicker, J ;

Clermont, G ;

Carcillo, J ;

Pinsky, MR .

CRITICAL CARE MEDICINE, 2001, 29 (07) :1303-1310

[3] Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock [J].

Annane, D ;

Sébille, V ;

Charpentier, C ;

Bollaert, PE ;

François, B ;

Korach, JM ;

Capellier, G ;

Cohen, Y ;

Azoulay, E ;

Troché, G ;

Chaumet-Riffaut, P ;

Bellissant, E .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (07) :862-871

[4] Efficacy and safety of recombinant human activated protein C for severe sepsis. [J].

Bernard, GR ;

Vincent, JL ;

Laterre, P ;

LaRosa, SP ;

Dhainaut, JF ;

Lopez-Rodriguez, A ;

Steingrub, JS ;

Garber, GE ;

Helterbrand, JD ;

Ely, EW ;

Fisher, CJ .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (10) :699-709

[5] Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. [J].

Brower, RG ;

Matthay, MA ;

Morris, A ;

Schoenfeld, D ;

Thompson, BT ;

Wheeler, A ;

Wiedemann, HP ;

Arroliga, AC ;

Fisher, CJ ;

Komara, JJ ;

Perez-Trepichio, P ;

Parsons, PE ;

Wolkin, R ;

Welsh, C ;

Fulkerson, WJ ;

MacIntyre, N ;

Mallatratt, L ;

Sebastian, M ;

McConnell, R ;

Wilcox, C ;

Govert, J ;

Thompson, D ;

Clemmer, T ;

Davis, R ;

Orme, J ;

Weaver, L ;

Grissom, C ;

Eskelson, M ;

Young, M ;

Gooder, V ;

McBride, K ;

Lawton, C ;

d'Hulst, J ;

Peerless, JR ;

Smith, C ;

Brownlee, J ;

Pluss, W ;

Kallet, R ;

Luce, JM ;

Gottlieb, J ;

Elmer, M ;

Girod, A ;

Park, P ;

Daniel, B ;

Gropper, M ;

Abraham, E ;

Piedalue, F ;

Glodowski, J ;

Lockrem, J ;

McIntyre, R .

NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (18) :1301-1308

[6] The epidemiology of the systemic inflammatory response [J].

Brun-Buisson, C .

INTENSIVE CARE MEDICINE, 2000, 26 (Suppl 1) :S64-S74

[7] Compliance with the Centers for Disease Control and Prevention antenatal culture protocol for preventing group B streptococcal neonatal sepsis [J].

Cheon-Lee, E ;

Amstey, MS .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1998, 179 (01) :77-79

[8] Economic evaluation of new therapies in critical illness [J].

Coughlin, MT ;

Angus, DC .

CRITICAL CARE MEDICINE, 2003, 31 (01) :S7-S16

[9] Medical progress: The pathophysiology and treatment of sepsis. [J].

Hotchkiss, RS ;

Karl, IE .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (02) :138-150

[10] Early goal-directed therapy in the treatment of severe sepsis and septic shock. [J].

Rivers, E ;

Nguyen, B ;

Havstad, S ;

Ressler, J ;

Muzzin, A ;

Knoblich, B ;

Peterson, E ;

Tomlanovich, M .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (19) :1368-1377

← 1 2 →