Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital

被引：210

作者：

Leavitt, Azita

Navon-Venezia, Shiri

Chmelnitsky, Inna

Schwaber, Mitchell J.

Carmeli, Yehuda

机构：

[1] Tel Aviv Sourasky Med Ctr, Div Epidemiol, IL-64239 Tel Aviv, Israel

[2] Tel Aviv Sourasky Med Ctr, Lab Mol Epidemiol & Antibiot Res, IL-64239 Tel Aviv, Israel

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 08期

关键词：

D O I：

10.1128/AAC.00299-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the bla(KPC-3) gene, while almost all other clones carried the bla(KPC-2) gene. This rapid dissemination of KPC outside the United States is worrisome.

引用

页码：3026 / 3029

页数：4

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