Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital

被引：213
作者：
Leavitt, Azita
Navon-Venezia, Shiri
Chmelnitsky, Inna
Schwaber, Mitchell J.
Carmeli, Yehuda
机构：
[1] Tel Aviv Sourasky Med Ctr, Div Epidemiol, IL-64239 Tel Aviv, Israel
[2] Tel Aviv Sourasky Med Ctr, Lab Mol Epidemiol & Antibiot Res, IL-64239 Tel Aviv, Israel
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 08期
关键词：
D O I：
10.1128/AAC.00299-07
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the bla(KPC-3) gene, while almost all other clones carried the bla(KPC-2) gene. This rapid dissemination of KPC outside the United States is worrisome.
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页码：3026 / 3029
页数：4
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