New and sensitive method for the spectrophotometric determination of certain tricyclic antidepressants

被引：15
|
作者：
Nagaraja, P [1 ]
Silwadi, MF [1 ]
Syed, AA [1 ]
机构：
[1] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India
来源：
MIKROCHIMICA ACTA | 2000年 / 135卷 / 3-4期
关键词：
Prussian Blue; tricylic antidepressant; dibenzazepine; spectrophotometry;
D O I：
10.1007/s006040070009
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A new, simple, and sensitive spectrophotometric method for the determination of certain tricyclic antidepressants, belonging to the dibenzazepine class of drugs, has been developed. The proposed method is based on the reaction of imipramine hydrochloride (IPH), desipramine hydrochloride (DPH), clomipramine hydrochloride (CPH), trimipramine maleate (TPM) or opipramol (OPP) with iron(III), and subsequent, reaction with ferricyanide in an acetic acid medium, to yield a blue product, with maximum absorption at 720-730 nm.
引用
收藏
页码：185 / 189
页数：5
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