The Negative Effect of Combining rhBMP-2 and Bio-Oss on Bone Formation for Maxillary Sinus Augmentation

被引：1

作者：

Kao, Daniel W. K. ^{[1
]}

Kubota, Atsushi

Nevins, Myron ^{[1
]}

Fiorellini, Joseph P. ^{[1
]}

机构：

[1] Univ Penn, Sch Dent Med, Dept Periodont, Philadelphia, PA 19104 USA

来源：

INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY | 2012年 / 32卷 / 01期

关键词：

ANORGANIC BOVINE BONE; MORPHOGENETIC PROTEIN-2; FLOOR AUGMENTATION; ELEVATION PROCEDURES; REGENERATED BONE; CASE SERIES; IMPLANTS; OSSEOINTEGRATION; DIFFERENTIATION;

D O I：

暂无

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Sinus augmentation with various bone graft materials may be required in the posterior maxilla. This study compared bone formation in a lateral window sinus augmentation with recombinant human bone morphogenetic protein 2/acellular collagen sponge (rhBMP-2/ACS) combined with Bio-Oss or Bio-Oss graft alone. Patients were assigned to treatment with either rhBMP-2/ACS + Bio-Oss or Bio-Oss alone. After a healing period, bone cores were harvested. Histologic specimens demonstrated that new bone formation was less in those who received rhBMP-2/ACS + Bio-Oss than those with Bio-Oss alone. This study indicated that the addition of rhBMP-2/ACS to Bio-Oss has a negative effect on bone formation. (Int J Periodontics Restorative Dent 2012;32:61-67.)

引用

页码：61 / 67

页数：7

共 29 条

[1] Bone regeneration in rabbit sinus lifting associated with bovine BMP [J].

Allegrini, S ;

Yoshimoto, M ;

Salles, MB ;

Konig, B .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2004, 68B (02) :127-131

[2]

BOYNE PJ, 1980, J ORAL SURG, V38, P613

[3] De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation [J].

Boyne, PJ ;

Lilly, LC ;

Marx, RE ;

Moy, PK ;

Nevins, M ;

Spagnoli, DB ;

Triplett, RG .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2005, 63 (12) :1693-1707

[4]

Boyne PJ, 1997, INT J PERIODONT REST, V17, P10

[5]

Cochran DL, 1997, INT J ORAL MAX IMPL, V12, P739

[6]

Del Fabbro M, 2004, INT J PERIODONT REST, V24, P565

[7]

Froum SJ, 2008, INT J PERIODONT REST, V28, P273

[8]

Froum SJ, 2006, INT J PERIODONT REST, V26, P543

[9]

Gapski R, 2006, INT J PERIODONT REST, V26, P59

[10] Comparison of implant survival following sinus floor augmentation procedures with implants placed in pristine posterior maxillary bone: a systematic review [J].

Graziani, F ;

Donos, N ;

Needleman, I ;

Gabriele, M ;

Tonetti, M .

CLINICAL ORAL IMPLANTS RESEARCH, 2004, 15 (06) :677-682

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