Use of the steroid backbone in the search for a range of compounds as potential inhibitors of the enzyme 17β-hydroxysteroid dehydrogenase (17β-HSD)

被引:0
|
作者
Soltani-Khankahdani, S. [1 ]
Dhanani, S. [2 ]
Owen, C. P. [1 ]
Ahmed, S. [1 ]
机构
[1] Kingston Univ, Dept Pharm, Sch Chem & Pharmaceut Sci, Kingston, Surrey, England
[2] Kingston Univ, Sch Life Sci, Kingston, Surrey, England
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:S38 / S38
页数:1
相关论文
共 50 条
  • [1] The synthesis and evaluation of a range of non-steroidal inhibitors of the type 3 isozyme of 17β-hydroxysteroid dehydrogenase (17β-HSD) through the derivatisation of the steroid backbone
    Acharya, P.
    Soltani-Khankahd, S.
    Owen, C.
    Ahmed, S.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2007, 59 : A30 - A30
  • [2] Synthesis, biochemical evaluation and molecular modelling of a range of compounds as potential inhibitors of the enzyme 17,6-hydroxysteroid clehydrogenase (17β-HSD)
    Abdulkadir, H.
    Lota, R.
    Owen, C. P.
    Dhanani, S.
    Ahmed, S.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2004, 56 : S61 - S61
  • [3] Characterization of PRAP as a novel 17β-hydroxysteroid dehydrogenase (17βHSD) enzyme.
    Risk, M
    Duan, WR
    Nelson, S
    Azhar, S
    Gibori, G
    BIOLOGY OF REPRODUCTION, 1999, 60 : 162 - 162
  • [4] Synthesis and biochemical evaluation of a series of phenyl ketones as potential inhibitors 17β-hydroxysteroid dehydrogenase (17β-HSD)
    Lota, R.
    Dhanani, S.
    Owen, C. P.
    Ahmed, S.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2005, 57 : S39 - S39
  • [5] Inhibition of 17β-hydroxysteroid dehydrogenase (17β-HSD) by imidazole-based compounds
    Olusanjo, Moniola S.
    Shahid, Imran
    Owen, Caroline P.
    Ahmed, Sabbir
    LETTERS IN DRUG DESIGN & DISCOVERY, 2008, 5 (01) : 48 - 51
  • [6] INHIBITORS OF 17-β-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17-β-HSD 3)
    Olusanjo, M. S.
    Ahmed, S.
    DRUGS OF THE FUTURE, 2009, 34 (07) : 555 - 563
  • [7] Inhibitors of human and rat testes microsomal 17β-hydroxysteroid dehydrogenase (17β-HSD) as potential agents for prostatic cancer
    Le Lain, R
    Nicholls, PJ
    Smith, HJ
    Maharlouie, FH
    JOURNAL OF ENZYME INHIBITION, 2001, 16 (01): : 35 - 45
  • [8] 17β-hydroxysteroid dehydrogenase (17β-HSD) in scleractinian corals and zooxanthellae
    Blomquist, CH
    Lima, PH
    Tarrant, AM
    Atkinson, MJ
    Atkinson, S
    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2006, 143 (04): : 397 - 403
  • [9] 17β-Hydroxysteroid dehydrogenase inhibitors
    Day, J. M.
    Tutill, H. J.
    Purohit, A.
    MINERVA ENDOCRINOLOGICA, 2010, 35 (02) : 87 - 108
  • [10] The molecular modelling of a series of steroidal and non-steroidal inhibitors of 17β-hydroxysteroid dehydrogenase (17β-HSD)
    Shahid, I.
    Lota, R.
    Owen, C. P.
    Ahmed, S.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2005, 57 : S39 - S39