A follow-up of four cases of nephrogenic systemic fibrosis: is gadolinium the specific trigger?

被引：12

作者：

Singh, M. ^{[1
]}

Davenport, A. ^{[2
]}

Clatworthy, I. ^{[3
]}

Lewin, J. ^{[3
]}

Deroide, F. ^{[4
]}

Hubbard, V. ^{[1
]}

Rustin, M. H. A. ^{[1
]}

机构：

[1] Royal Free Hosp, Dept Dermatol, London NW3 2QG, England

[2] Royal Free Hosp, Dept Nephrol, London NW3 2QG, England

[3] Royal Free Hosp, Dept Electron Microscopy, London NW3 2QG, England

[4] Royal Free Hosp, Dept Histopathol, London NW3 2QG, England

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2008年 / 158卷 / 06期

关键词：

gadolinium; magnetic resonance imaging; nephrogenic fibrosing dermopathy; nephrogenic systemic fibrosis;

D O I：

10.1111/j.1365-2133.2008.08506.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We originally reported four patients with nephrogenic systemic fibrosis (NSF) in the British Journal of Dermatology in 2003, and now present an update of their outcome. All four patients (three females and one male) presented within a six month period at our institution, and had received gadolinium contrast agents prior to disease onset. Two patients with functioning renal transplants had limited cutaneous disease, two patients maintained on haemodialysis had more severe disease and died one year after disease onset. Gadolinium deposition was demonstrated in lesional skin of one patient using electron microscopy and energy dispersive spectroscopy.

引用

页码：1358 / 1362

页数：5

共 16 条

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