Cisplatin, fluorouracil and vinorelbine in recurrent or metastatic squamous bead and neck carcinomas

被引：0

作者：

Berrocal, A ^{[1
]}

Safont, MJ ^{[1
]}

Albert, A ^{[1
]}

Camps, C ^{[1
]}

Nogueron, E ^{[1
]}

Muñoz, J ^{[1
]}

Bagan, JV ^{[1
]}

机构：

[1] Hosp Gen Univ Valencia, Med Oncol Unit, Valencia, Spain

来源：

1ST WORLD CONGRESS ON HEAD AND NECK ONCOLOGY | 1998年

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

To assess response and toxicity of the combination of cisplatin. fluorouracil and vinorelbine in recurrent and/or metastatic squamous cell carcinoma of the head and neck we treated 23 patients with this drugs Therapeutic scheme was cisplatin 100 mg/m(2) on day one, 5-fluorouracil 650 mg/m(2) days one to five and vinorelbine 20 mg/m(2) days one and eight. We have observed 36% partial response rate and 21% stable disease. Actuarial median survival has been 8.74 months. Main toxicity has been haematological specially on red cells and neutropenia. In conclusion this combination offers a response rate similar to standar chemotherapy with a moderate toxicity.

引用

页码：1027 / 1030

页数：4