Chronopotentiometric studies of phosphatidylcholine bilayers modified by ergosterol

被引：10
作者：
Naumowicz, Monika [1 ]
Petelska, Aneta Dorota [1 ]
Figaszewski, Zbigniew Artur [1 ,2 ]
机构：
[1] Univ Bialystok, Inst Chem, PL-15443 Bialystok, Poland
[2] Univ Warsaw, Lab Electrochem Power Sources, Fac Chem, PL-02093 Warsaw, Poland
来源：
STEROIDS | 2011年 / 76卷 / 10-11期
关键词：
Chronopotentiometry; Bilayer lipid membrane; Ergosterol; Phosphatidylcholine; Capacitance; Resistance; PLANT STEROLS; DIMYRISTOYLPHOSPHATIDYLCHOLINE BILAYERS; WATER PERMEABILITY; IMPEDANCE ANALYSIS; CHOLESTEROL; MEMBRANE; DYNAMICS; ELECTROPORATION; LECITHIN; SYSTEM;
D O I：
10.1016/j.steroids.2011.05.009
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We have monitored the effect of ergosterol on electrical capacitance and electrical resistance of the phosphatidylcholine bilayer membranes using chronopotentiometry method. The chronopotentiometric characteristic of the bilayers depends on constant-current flow through the membranes. For low current values, no electroporation takes place and the membrane voltage rises exponentially to a constant value described by the Ohm's law. Based on these kinds of chronopotentiometric curves, a method of the membrane capacitance and the membrane resistance calculations is presented. (C) 2011 Elsevier Inc. All rights reserved.
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页码：967 / 973
页数：7
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