aza-annulation of tetrahydroisoquinoline derived enamines:: Efficient and convergent routes to novel functionalized benzo[a]quinolizin-4-ones and pyrimido[6,1-a]isoquinoline derivatives
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作者:
Chakrabarti, S
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机构:Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India
Chakrabarti, S
Srivastava, MC
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机构:Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India
Srivastava, MC
Ila, H
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Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, IndiaIndian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India
Ila, H
[1
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Junjappa, H
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机构:Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India
Junjappa, H
机构:
[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India
[2] BioOrgan & Appl Mat Pvt Ltd, Bangalore 560058, Karnataka, India
The 1,2,3,4-tetrahydroisoquinoline derived push-pull enaminones and nitroenamine have been investigated in aza-annulation reactions with various 1,3-biselectrophiles leading to the synthesis of novel functionalized benzo[a]quinolizin-4-ones and pyrimido[6,1-a]isoquinoline derivatives.