PATHOPHYSIOLOGIC RELATIONSHIPS BETWEEN OXIDATIVE STRESS AND ATHEROSCLEROSIS

被引：12
作者：
Silva, Danielle da Costa [1 ]
Cerchiaro, Giselle [1 ]
Honorio, Kathia M. [1 ,2 ]
机构：
[1] Univ Fed ABC, Ctr Ciencias Nat & Humanas, BR-09210170 Santo Andre, SP, Brazil
[2] Univ Sao Paulo, Escola Artes Ciencias & Humanidades, BR-03828000 Sao Paulo, Brazil
来源：
QUIMICA NOVA | 2011年 / 34卷 / 02期
关键词：
oxidative stress; nitric oxide; atherosclerosis; NITRIC-OXIDE; CARDIOVASCULAR INJURY; ENDOTHELIAL-CELLS; INFLAMMATION; HYPERTENSION; METABOLISM; CHOLESTEROL; MACROPHAGES; EXPRESSION;
D O I：
10.1590/S0100-40422011000200024
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
PATHOPHYSIOLOGIC RELATIONSHIPS BETWEEN OXIDATIVE STRESS AND ATHEROSCLEROSIS. Oxidative stress is the result of an imbalance between oxidant and antioxidant species, with predominance of oxidative species with harmful action of reactive oxygen species (nROS) and reactive nitrogen species (nRNS) on cells. Changes in the levels of nitric oxide (NO center dot) can be the cause and/or a result of various pathophysiological processes. The main objective of this review is to address the relationship between oxidative stress and atherosclerosis in order to better understand the main features of this disease.
引用
收藏
页码：300 / 305
页数：6
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