Synthesis of 5-substituted 2-(4-or 3-methoxyphenyl)-4(1H)-quinolones

被引：12
作者：
Pain, C
Célanire, S
Guillaumet, G
Joseph, B
机构：
[1] Univ Lyon 1, CNRS, UMR 5622, Lab Chim Organ 1, F-69622 Villeurbanne, France
[2] Univ Orleans, CNRS, UMR 6005, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
来源：
TETRAHEDRON | 2003年 / 59卷 / 48期
关键词：
quinolones; Stille reaction; Suzuki reaction; SNAr; aminations;
D O I：
10.1016/j.tet.2003.09.094
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Substituted 7-methoxy-2-(4- or 3-methoxyphenyl)-4(1H)-quinolones 8-17 have been synthesised in good yields from the corresponding 7-methoxy-2-(4- or 3-methoxyphenyl)-5-trifluoromethanesulfonate-4(1H)-quinolones 7 via palladium-mediated cross-coupling reactions or aromatic nucleophilic substitution (SNA(Ar)) reactions. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：9627 / 9633
页数：7
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