Long-term skin damage due to chemical weapon exposure

被引:25
作者
Firooz, Alireza [1 ]
Sadr, Bardia [1 ]
Davoudi, Seyed M. [2 ]
Nassiri-Kashani, Mansour [1 ]
Panahi, Yunes [3 ]
Dowlati, Yahya [1 ]
机构
[1] Univ Tehran Med Sci, Ctr Res & Training Skin Dis & Leprosy, Tehran, Iran
[2] Baqyiatallah Univ Med Sci, Dept Dermatol, Tehran, Iran
[3] Baqyiatallah Univ Med Sci, Res Ctr Chem Injuries, Tehran, Iran
关键词
Mustard; blister; scar; angioma; skin cancer; SULFUR MUSTARD EXPOSURE; TRANSEPIDERMAL WATER-LOSS; IRANIAN VETERANS; WARTIME EXPOSURE; GAS; LESIONS; MANIFESTATIONS; COMPLICATIONS; BETAMETHASONE; PRURITUS;
D O I
10.3109/15569527.2010.529547
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Sulfur mustard (2,2-dichlorodiethyl sulfide: SM), the protagonist of vesicant chemical weapons, was first used in July 1917. Despite prohibition of its production and use by international conventions, it has been used in several conflicts. More than 100,000 soldiers and civilians were injured due to SM exposure during Iran--Iraq war (1980--1988). The acute skin lesions consist of erythema, edema, and blisters. Skin xerosis and pruritus, pigmentation disorders, scars, and cherry angiomas are among the most common long-term skin lesions after contact with SM. Although SM is a well-known carcinogenic substance, skin cancers are rarely reported.</.
引用
收藏
页码:64 / 68
页数:5
相关论文
共 34 条
[1]   Comparison of early and late toxic effects of sulfur mustard in Iranian veterans [J].
Balali-Mood, Mahdi ;
Hefazi, Mehrdad .
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2006, 99 (04) :273-282
[2]  
Davoudi S. M., 2008, Iranian Journal of Dermatology, V11, P151
[3]   Comparative study of skin sebum and elasticity level in patients with sulfur mustard-induced dermatitis and healthy controls [J].
Davoudi, Seyyed Masoud ;
Sadr, Bardia ;
Hayatbakhsh, Mohammad R. ;
Keshavarz, Saeed ;
Shohrati, Majid ;
Naghizadeh, Mohammad Mehdi ;
Babakoohi, Shahab ;
Rashighi-Firouzabadi, Mehdi ;
Firooz, Alireza .
SKIN RESEARCH AND TECHNOLOGY, 2010, 16 (02) :237-242
[4]   Skin hydration and transepidermal water loss in patients with a history of sulfur mustard contact: a case-control study [J].
Davoudi, Seyyed Masoud ;
Keshavarz, Saeed ;
Sadr, Bardia ;
Shohrati, Majid ;
Naghizadeh, Mohammad Mehdi ;
Farsinejad, Khalil ;
Rashighi-Firouzabadi, Mehdi ;
Zartab, Hamed ;
Firooz, Alireza .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2009, 23 (08) :940-944
[5]   Urinary and cutaneous complications of sulphur mustard poisoning preceding pulmonary and ocular involvement: an unusual sequence of symptoms [J].
Emadi, S. N. ;
Moeineddin, F. ;
Sorush, M. R. .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2009, 34 (05) :E7-E10
[6]   Late cutaneous manifestations 14 to 20 years after wartime exposure to sulfur mustard gas: A long-term investigation [J].
Emadi, Seyed Naser ;
Mortazavi, Mohammadreza ;
Mortazavi, Hossein .
ARCHIVES OF DERMATOLOGY, 2008, 144 (08) :1059-1061
[7]   Mustard gas scarring with specific pigmentary, trophic and vascular charactristics (case report, 16-year post-exposure) [J].
Emadi, Seyed Naser ;
Hosseini-khalili, Allreza ;
Soroush, Mohammad Reza ;
Davoodi, Seyed Masoud ;
Aghamiri, Seyed Samad .
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2008, 69 (03) :574-576
[8]  
Feister AJ., 1991, Medical defense against mustard gas: toxic mechanisms and pharmacological implications
[9]  
FEKRI A, 1996, J KERMAN MED SCI U, V3, P108
[10]   Eruptive melanocytic nevi and cherry angiomas secondary to exposure to sulfur mustard gas [J].
Firooz, A ;
Komeili, A ;
Dowlati, Y .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 40 (04) :646-647