Increased 68Ga-FAPI Uptake in Neurofibromatosis in a Patient With Pleomorphic RhabdomyosarcomaY

被引：12

作者：

Wu, Junhao

Wang, Yingwei

Zhang, Chunyin

机构：

[1] Southwest Med Univ, Affiliated Hosp, Dept Nucl Med, Luzhou, Sichuan, Peoples R China

[2] Nucl Med & Mol Imaging Key Lab Sichuan Prov, Luzhou, Sichuan, Peoples R China

[3] Workstn Sichuan Prov, Luzhou, Sichuan, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2021年 / 46卷 / 12期

关键词：

neurofibromatosis; fibroblast activation protein; Ga-68-FAPI; PET/CT;

D O I：

10.1097/RLU.0000000000003716

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 48-year-old man presented with a painless enlarging mass on his right thigh for 2 months. He had a history of neurofibromatosis. MRI showed a mass in his right thigh. Malignant tumor was suspected. He was enrolled in the clinical trial of 68Ga-FAPI in solid tumors. Multiple increased FAPI uptake was observed in the right thigh mass, lung, and mediastinal lymph nodes, which were confirmed being pleomorphic rhabdomyosarcoma by biopsy. In addition, widespread metabolic activity was also observed in his cutaneous fibroma nodules. This case showed that benign neurofibromatosis can cause FAPI uptake. © 2020 Wolters Kluwer Health, Inc. All rights reserved.

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页码：1018 / 1019

页数：2

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