Glomerular filtration rate abnormalities in sickle cell disease

被引：11
作者：
Afangbedji, Nowah [1 ]
Jerebtsova, Marina [2 ]
机构：
[1] Howard Univ, Dept Physiol & Biophys, Washington, DC USA
[2] Howard Univ, Dept Microbiol, Washington, DC 20059 USA
来源：
FRONTIERS IN MEDICINE | 2022年 / 9卷
关键词：
sickle cell disease; glomerular filtration; hyperfiltration; chronic kidney disease; sickle cell nephropathy; biomarkers; CHRONIC KIDNEY-DISEASE; RENAL ABNORMALITIES; ANEMIA; HYPERFILTRATION; RISK; NEPHROPATHY; MORTALITY; CHILDREN; ADULTS; HYDROXYUREA;
D O I：
10.3389/fmed.2022.1029224
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Sickle cell disease (SCD) is a group of inherited blood disorders affecting the beta-globin gene, resulting in the polymerization of hemoglobin and subsequent sickling of the red blood cell. Renal disease, the most common complication in SCD, begins in childhood with glomerular hyperfiltration and then progresses into albuminuria, a fast decline of glomerular filtration, and renal failure in adults. This mini-review focuses on glomerular filtration abnormalities and the mechanisms of hyperfiltration, explores genetic modifiers and methods of estimating glomerular filtration rates, and examines novel biomarkers of glomerular filtration in SCD.
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共 97 条
[1]   Clinical and genetic factors are associated with kidney complications in African children with sickle cell anaemia [J].
Adebayo, Oyindamola Christiana ;
Betukumesu, DieuMerci Kabasele ;
Nkoy, Agathe Bikupe ;
Adesoji, Oluyomi Modupe ;
Ekulu, Pepe Mfutu ;
Van den Heuvel, Lambertus P. ;
Levtchenko, Elena N. ;
Labarque, Veerle .
BRITISH JOURNAL OF HAEMATOLOGY, 2022, 196 (01) :204-214
[2]   The kidney in sickle hemoglobinopathies [J].
Airy, Medha ;
Eknoyan, Garabed .
CLINICAL NEPHROLOGY, 2017, 87 (02) :55-68
[3]   Genetic modifiers of fetal hemoglobin affect the course of sickle cell disease in patients treated with hydroxyurea [J].
Allard, Pierre ;
Alhaj, Nareen ;
Lobitz, Stephan ;
Cario, Holger ;
Jarisch, Andreas ;
Grosse, Regine ;
Oevermann, Lena ;
Hakimeh, Dani ;
Tagliaferri, Laura ;
Kohne, Elisabeth ;
Kopp-Schneider, Annette ;
Kulozik, Andreas E. ;
Kunz, Joachim B. .
HAEMATOLOGICA, 2022, 107 (07) :1577-1588
[4]   RENAL ABNORMALITIES IN SICKLE-CELL DISEASE [J].
ALLON, M .
ARCHIVES OF INTERNAL MEDICINE, 1990, 150 (03) :501-504
[5]   Renal Function in Children Suffering from Sickle Cell Disease: Challenge of Early Detection in Highly Resource-Scarce Settings [J].
Aloni, Michel Ntetani ;
Ngiyulu, Rene Makwala ;
Gini-Ehungu, Jean-Lambert ;
Nsibu, Celestin Ndosimao ;
Ekila, Mathilde Bothale ;
Lepira, Francois Bompeka ;
Nseka, Nazaire Mangani .
PLOS ONE, 2014, 9 (05)
[6]   MEASUREMENT OF GLOMERULAR-FILTRATION RATE IN HOMOZYGOUS SICKLE-CELL DISEASE - A COMPARISON OF CR-51 EDTA CLEARANCE, CREATININE CLEARANCE, SERUM CREATININE AND BETA-2 MICROGLOBULIN [J].
APARICIO, SAJ ;
MOJIMINIYI, S ;
KAY, JDS ;
SHEPSTONE, BJ ;
DECEULAER, K ;
SERJEANT, GR .
JOURNAL OF CLINICAL PATHOLOGY, 1990, 43 (05) :370-372
[7]   Determination of the best method to estimate glomerular filtration rate from serum creatinine in adult patients with sickle cell disease: a prospective observational cohort study [J].
Arlet, Jean-Benoit ;
Ribeil, Jean-Antoine ;
Chatellier, Gilles ;
Eladari, Dominique ;
De Seigneux, Sophie ;
Souberbielle, Jean-Claude ;
Friedlander, Gerard ;
de Montalembert, Marianne ;
Pouchot, Jacques ;
Prie, Dominique ;
Courbebaisse, Marie .
BMC NEPHROLOGY, 2012, 13
[8]   MYH9 and APOL1 are both associated with sickle cell disease nephropathy [J].
Ashley-Koch, Allison E. ;
Okocha, Emmanuel C. ;
Garrett, Melanie E. ;
Soldano, Karen ;
De Castro, Laura M. ;
Jonassaint, Jude C. ;
Orringer, Eugene P. ;
Eckman, James R. ;
Telen, Marilyn J. .
BRITISH JOURNAL OF HAEMATOLOGY, 2011, 155 (03) :386-394
[9]   Predictors of renal function progression in adults with homozygous sickle cell disease [J].
Asnani, Monika ;
Serjeant, Graham ;
Royal-Thomas, Tamika ;
Reid, Marvin .
BRITISH JOURNAL OF HAEMATOLOGY, 2016, 173 (03) :461-468
[10]   Determining Glomerular Filtration Rate in Homozygous Sickle Cell Disease: Utility of Serum Creatinine Based Estimating Equations [J].
Asnani, Monika R. ;
Lynch, O'Neil ;
Reid, Marvin E. .
PLOS ONE, 2013, 8 (07)
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