Palladium-Catalyzed Oxidative Heck-Type Alkylation/Aryl Migration/Desulfonylation between Alkenes with α-Carbonyl Alkyl Bromides

被引：57
作者：
Fan, Jian-Hong [1 ]
Yang, Ji [1 ]
Song, Ren-Jie [1 ]
Li, Jin-Heng [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
来源：
ORGANIC LETTERS | 2015年 / 17卷 / 04期
关键词：
ACTIVATED ALKENES; ENANTIOSELECTIVE CONSTRUCTION; TERMINAL ALKENES; BOND FORMATION; C(SP3)H BOND; OXINDOLES; DIFUNCTIONALIZATION; CYCLIZATION; ARYL; TRIFLUOROMETHYLATION;
D O I：
10.1021/ol503660a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new Pd(II)-catalyzed alkene oxidative difunctionalization initiated by Heck insertion has been developed for the selective synthesis of acyclic and cyclic all-carbon quaternary stereocenters, which achieves an oxidative Heck-type alkylation, aryl migration, and desulfonylation sequence and represents a different input from those previously used Heck coupling in synthesis is reported.
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收藏
页码：836 / 839
页数：4
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