Evaluation of Dry Eye

被引：118
作者：
McGinnigle, Samantha [1 ]
Naroo, Shehzad A. [1 ]
Eperjesi, Frank [1 ]
机构：
[1] Aston Univ, Sch Life & Hlth Sci, Ophthalm Res Grp, Birmingham B4 7ET, W Midlands, England
来源：
SURVEY OF OPHTHALMOLOGY | 2012年 / 57卷 / 04期
关键词：
dry eye; tear quality; ocular surface; tear secretion; tear break up; osmolarity; evaporation; lipid layer; staining; MEIBOMIAN GLAND DYSFUNCTION; TEAR BREAK-UP; OCULAR SURFACE DISEASE; FUNCTIONAL VISUAL-ACUITY; EPIDERMAL-GROWTH-FACTOR; OPTICAL COHERENCE TOMOGRAPHY; MENISCUS HEIGHT MEASUREMENT; SCANNING LASER MICROSCOPY; STABILITY ANALYSIS SYSTEM; HIGHER-ORDER ABERRATIONS;
D O I：
10.1016/j.survophthal.2011.11.003
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Dry eye is a common yet complex condition. Intrinsic and extrinsic factors can cause dysfunction of the lids, lacrimal glands, meibomian glands, ocular surface cells, or neural network. These problems would ultimately be expressed at the tear film-ocular surface interface. The manifestations of these problems are experienced as symptoms such as grittiness, discomfort, burning sensation, hyperemia, and secondary epiphora in some cases. Accurate investigation of dry eye is crucial to correct management of the condition. Techniques can be classed according to their investigation of tear production, tear stability, and surface damage (including histological tests). The application, validity, reliability, compatibility, protocols, and indications for these are important. The use of a diagnostic algorithm may lead to more accurate diagnosis and management. The lack of correlation between signs and symptoms seems to favor tear film osmolarity, an objective biomarker, as the best current clue to correct diagnosis. (Surv Ophthalmol 57:293-316, 2012. (c) 2012 Elsevier Inc. All rights reserved.)
引用
收藏
页码：293 / 316
页数：24
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